Sluyser M, Evers P, Hilgers J
Cancer Lett. 1985 Jun;27(2):207-13. doi: 10.1016/0304-3835(85)90109-0.
Large marker chromosomes were found in 2 hormone-independent (HI) GR mouse mammary tumors, i.e. a tumor (TSl 75) that was already HI at the first transplantation, and a tumor (TSl 66) that became HI at the 19th passage. These marker chromosomes appear to be translocations to distal and proximal ends of chromosome 1, respectively. The translocation in tumor TSl 66 may be t(15:1).
在2个激素非依赖性(HI)GR小鼠乳腺肿瘤中发现了大标记染色体,即一个在首次移植时就已为HI的肿瘤(TSl 75),以及一个在第19代时变为HI的肿瘤(TSl 66)。这些标记染色体似乎分别是1号染色体远端和近端的易位。肿瘤TSl 66中的易位可能是t(15:1)。