Sato Hiroshi, Maruyama Riruke, Kishi Hirofumi, Higashi Koichiro, Yuki Mika, Nagami Haruhiko, Tabara Hideki
Izumo Tokushukai Hospital Izumo Shimane Japan.
J Gen Fam Med. 2024 Dec 9;26(2):163-165. doi: 10.1002/jgf2.762. eCollection 2025 Mar.
A 77-year-old woman on regular hemodialysis was admitted due to purpura on her extremities, elevated C-reactive protein (CRP), D-dimer, and syncope attack. Despite hospitalization and treatment, her purpura got worse, and a skin biopsy revealed cutaneous small vessel vasculitis (CSVV). No apparent cause could be pointed out for CSVV. Her purpura had deteriorated until we started treatment with prednisolone (PSL). We later confirmed that she had received her seventh COVID-19 vaccination before the onset of purpura on her extremities. In this case, the highlight is that even the seventh dose of the COVID-19 vaccination could potentially induce CSVV.
一名77岁接受规律血液透析的女性因四肢出现紫癜、C反应蛋白（CRP）及D-二聚体升高和晕厥发作入院。尽管住院治疗，但她的紫癜仍加重，皮肤活检显示为皮肤小血管血管炎（CSVV）。未发现CSVV的明显病因。在开始使用泼尼松龙（PSL）治疗前，她的紫癜病情持续恶化。后来我们确认她在四肢出现紫癜之前接种了第七剂新冠疫苗。在这种情况下，值得注意的是，即使是第七剂新冠疫苗也可能诱发CSVV。
