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双侧乳腺癌手术后腋窝异位乳腺癌:一例报告及文献复习

Ectopic Breast Cancer in the Axilla After Bilateral Breast Cancer Surgery: A Case Report and Literature Review.

作者信息

Ishige Hiroyuki, Mukouyama Yimi, Kosaka Taijiro, Shiozawa Satoshi, Sato Noritoshi

机构信息

Department of Breast Surgery, Saku Central Hospital, Saku, JPN.

Department of Pathology, Saku Central Hospital, Saku, JPN.

出版信息

Cureus. 2025 Feb 6;17(2):e78639. doi: 10.7759/cureus.78639. eCollection 2025 Feb.

Abstract

Ectopic breast cancer (EBC) is a rare condition, and there have been no reports of axillary EBC as a third primary breast cancer after bilateral pectoral breast cancer (PBC) surgery. A woman presented with a mass in her axilla, which was located just beneath the skin. On ultrasound (US) examination, it appeared oval-shaped with uniform internal echoes and relatively clear boundaries. Pathologically, it was an oval-shaped, well-defined tumor and was diagnosed as encapsulated papillary carcinoma with invasion. EBC rises directly under the axillary skin, where axillary ectopic breast tissue exists. This area is not generally included in the resection field during mastectomy and axillary lymph node dissection, as illustrated in this case. US findings of EBC do not consistently show an irregularly shaped mass with indistinct boundaries, as these depend on the tumor's histological structure, similar to PBC. When axillary masses are observed, it is crucial to consider the possibility of EBC based on their superficial location in the axilla and to predict histological architecture and type from US findings, similar to the approach for PBC.

摘要

异位乳腺癌(EBC)是一种罕见疾病,目前尚无关于双侧胸肌乳腺癌(PBC)手术后腋窝EBC作为第三种原发性乳腺癌的报道。一名女性腋窝出现肿物,位于皮下。超声(US)检查显示,肿物呈椭圆形,内部回声均匀,边界相对清晰。病理检查显示,这是一个椭圆形、边界清晰的肿瘤,诊断为浸润性包膜乳头状癌。EBC直接发生于腋窝皮肤下方,此处存在腋窝异位乳腺组织。如本病例所示,在乳房切除术和腋窝淋巴结清扫术中,该区域通常不包括在切除范围内。与PBC一样,EBC的US表现并不总是显示边界不清的不规则肿物,这取决于肿瘤的组织结构。当观察到腋窝肿物时,基于其在腋窝的浅表位置考虑EBC的可能性,并根据US表现预测组织学结构和类型,这一点至关重要,与PBC的处理方法类似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/679d/11890161/c2c0e85bcb33/cureus-0017-00000078639-i01.jpg

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