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新型冠状病毒感染后迟发性荨麻疹和多形红斑样皮疹

Late-Onset Urticarial and Erythema Multiforme-Like Eruption Following SARS-CoV-2 Infection.

作者信息

Suening Barbara S, Boyko Molly E, Starr Alicia J, Glover M Holly

机构信息

Dermatology, University of Central Florida College of Medicine, Gainesville, USA.

Dermatology, Edward Via College of Osteopathic Medicine, Spartanburg, USA.

出版信息

Cureus. 2025 Feb 5;17(2):e78547. doi: 10.7759/cureus.78547. eCollection 2025 Feb.

Abstract

Although SARS-CoV-2 primarily targets the upper respiratory system, its evolving clinical profile has revealed a diverse range of manifestations across multiple organ systems. Emerging evidence increasingly highlights various skin manifestations associated with the virus. This report details the case of a patient who developed a rapidly progressive urticarial dermatosis, characterized by both urticarial and erythema multiforme-like features, five weeks after a SARS-CoV-2 infection. Our objective is to underscore the histologic patterns of late-onset skin eruptions related to SARS-CoV-2, focusing on dermatological complications that can arise beyond the acute phase of the infection.

摘要

尽管严重急性呼吸综合征冠状病毒2(SARS-CoV-2)主要侵袭上呼吸道系统,但其不断演变的临床特征显示出在多个器官系统中存在多种表现形式。越来越多的新证据凸显了与该病毒相关的各种皮肤表现。本报告详细介绍了一名患者的病例,该患者在感染SARS-CoV-2五周后出现了一种迅速进展的荨麻疹样皮肤病,其特征兼具荨麻疹和多形红斑样特征。我们的目的是强调与SARS-CoV-2相关的迟发性皮肤疹的组织学模式,重点关注感染急性期之后可能出现的皮肤并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c78c/11887517/2b2af51a731c/cureus-0017-00000078547-i01.jpg

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