Kleinhans E, Baumeister R G, Hahn D, Siuda S, Büll U, Moser E
Eur J Nucl Med. 1985;10(7-8):349-52. doi: 10.1007/BF00251310.
To quantitate visual findings in lymphoscintigraphy with 99mTc-labeled stannous sulfur colloids, a numeric index of transport kinetics was designed by combining visual assessment of five criteria: temporal and spatial distribution of the radionuclide, appearance time of lymph nodes, and graded visualization of lymph nodes and vessels. For assessment, scores were used ranging from 0 to 9. Thus, the resulting transport index (TI) ranged from 0 (normal) to 45 (pathological). TI in healthy extremities was less than 10. Lymphoscintigraphy was performed routinely in healthy lower extremities to ensure normal drainage before transplantation. In 122 investigations of upper and lower extremities, TI was found to be very sensitive (97.4%). Specificity was 90.3%. An interobserver study in 179 investigations revealed a high correlation (r = 0.96). A total of 23 patients underwent autologous lymphatic transplantation. The average decrease of TI was 5.9: 31.1 before and 25.2 after transplantation. This decrease of TI was correlated with a marked decrease of the volumes of the extremities (from 3423 ml to 2580 ml). Changes in TI and volume were significant (p less than 0.05). This method of evaluation has proved to be very sensitive, reproducible, and able to measure the transport capacity of only two or three transplanted lymph collectors.
为了定量评估用99mTc标记的硫化亚锡胶体进行淋巴闪烁显像的视觉结果，通过综合视觉评估五个标准设计了一个运输动力学数字指数：放射性核素的时间和空间分布、淋巴结的出现时间以及淋巴结和淋巴管的分级显像。评估时使用的分数范围为0至9。因此，所得的运输指数（TI）范围为0（正常）至45（病理）。健康肢体的TI小于10。在健康下肢常规进行淋巴闪烁显像，以确保移植前引流正常。在122例上下肢检查中，发现TI非常敏感（97.4%）。特异性为90.3%。在179例检查中的观察者间研究显示出高度相关性（r = 0.96）。共有23例患者接受了自体淋巴移植。TI的平均下降为5.9：移植前为31.1，移植后为25.2。TI的这种下降与肢体体积的显著减少相关（从3423毫升降至2580毫升）。TI和体积的变化具有显著性（p小于0.05）。这种评估方法已被证明非常敏感、可重复，并且能够测量仅两三个移植淋巴收集器的运输能力。
