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氙-133在小鼠膀胱中的分布。

Distribution of xenon-133 in mice from the urinary bladder.

作者信息

Eldrup J, Krogsgaard O W, Nielsen S L

出版信息

Eur J Nucl Med. 1985;10(7-8):369-72. doi: 10.1007/BF00251315.

DOI:10.1007/BF00251315
PMID:4006980
Abstract

The distribution of 133Xe from the bladder was investigated in sliced mice at autoradiography and quantitatively by counting tissue samples from the abdomen and thoracic cavity. Xenon is a highly diffusible inert gas that passes the bladder urothelium. In living mice activity could be seen in the intra-abdominal fat, liver and kidneys; the activity in the kidneys depended on reflux through the ureters. The xenon gas was found in the highest concentration in the lungs where it is expired. The study confirms the assumption that instillation of xenon in the bladder can be used as an indicator for permeability and flow in the wall of the urinary bladder.

摘要

通过放射自显影技术并对腹部和胸腔组织样本进行计数定量,研究了切片小鼠膀胱中¹³³Xe的分布情况。氙是一种高度可扩散的惰性气体,可透过膀胱尿路上皮。在活体小鼠中,可在腹腔脂肪、肝脏和肾脏中观察到放射性;肾脏中的放射性取决于通过输尿管的反流情况。在肺部发现氙气浓度最高,它在肺部呼出。该研究证实了以下假设:向膀胱内注入氙可作为膀胱壁通透性和血流的指标。

相似文献

1
Distribution of xenon-133 in mice from the urinary bladder.氙-133在小鼠膀胱中的分布。
Eur J Nucl Med. 1985;10(7-8):369-72. doi: 10.1007/BF00251315.
2
[Xenon exhalation measurements in the diagnosis of bladder diseases].[氙气呼出量测量在膀胱疾病诊断中的应用]
Urologe A. 1975 Jan;14(1):38-40.
3
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Xenon-133 resorption in urinary bladder: functional diagnosis of bladder epithelium.氙-133在膀胱中的重吸收:膀胱上皮的功能诊断
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Penile xenon (133Xe) washout: a rapid method of screening for vasculogenic impotence.阴茎氙(133Xe)清除率:一种筛查血管性阳痿的快速方法。
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引用本文的文献

1
Urinary bladder blood flow. I. Comparison of clearance of locally injected 99mtechnetium pertechnate and radioactive microsphere technique in dogs.膀胱血流。I. 犬局部注射高锝[99mTc]酸盐清除率与放射性微球技术的比较。
Urol Res. 1990;18(3):223-6. doi: 10.1007/BF00295852.
2
Rate of urinary bladder blood flow evaluated by 133Xe washout and radioactive microspheres in pigs.通过133Xe洗脱法和放射性微球评估猪膀胱血流速率。
Urol Res. 1991;19(6):387-91. doi: 10.1007/BF00310155.

本文引用的文献

1
[Xenon exhalation measurements in the diagnosis of bladder diseases].[氙气呼出量测量在膀胱疾病诊断中的应用]
Urologe A. 1975 Jan;14(1):38-40.
2
The mammalian urinary bladder: an accommodating organ.哺乳动物的膀胱:一个适应性器官。
Biol Rev Camb Philos Soc. 1975 May;50(2):215-46. doi: 10.1111/j.1469-185x.1975.tb01057.x.