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[氙气呼出量测量在膀胱疾病诊断中的应用]

[Xenon exhalation measurements in the diagnosis of bladder diseases].

作者信息

Völter D, Weisswange V, Ziegler H, Schubert G E

出版信息

Urologe A. 1975 Jan;14(1):38-40.

PMID:1114522
Abstract

Using an exhalameter radioactive marked Xenon, absorbed following bladder instillation, was determined in the expired air of 111 patients. In 65 of these patients the usual criteria in the diagnosis of bladder diseases were simultaneously ascertained. The functional disturbances of the epithelium of the bladder obtained through 133Xenon exhalation measurements did not correlate with the morphological changes. Especially in the so-called "Reizblase" (irritable bladder) functional disturbances were found without a morphological equivalent. Compared with the low Xenon exhalation found in patients with healthy urinary bladders there is a marked Xenon exhalation increase (10-15 times) in inflammation of the urinary bladder. In our opinion Xenon exhalation measurements is at the present time the most sensitive method for determining inflammatory diseases of the urinary bladder.

摘要

使用呼气测定仪,对111例患者呼出气体中的放射性标记氙进行了测定,这些氙是在膀胱灌注后被吸收的。其中65例患者同时确定了膀胱疾病诊断的常用标准。通过133氙呼气测量获得的膀胱上皮功能障碍与形态学变化无关。特别是在所谓的“激惹膀胱”中,发现了功能障碍但无形态学对应改变。与健康膀胱患者呼出的低氙含量相比,膀胱炎症时氙呼出量明显增加(10 - 15倍)。我们认为,目前氙呼气测量是确定膀胱炎性疾病最敏感的方法。

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1
[Xenon exhalation measurements in the diagnosis of bladder diseases].[氙气呼出量测量在膀胱疾病诊断中的应用]
Urologe A. 1975 Jan;14(1):38-40.
2
Xenon-133 resorption in urinary bladder: functional diagnosis of bladder epithelium.氙-133在膀胱中的重吸收:膀胱上皮的功能诊断
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Leaky urothelium and/or vesical ischemia enable urinary potassium to cause idiopathic urgency/frequency syndrome and urge incontinence.尿路上皮渗漏和/或膀胱缺血使尿钾引发特发性尿急/尿频综合征和急迫性尿失禁。
Int Urogynecol J Pelvic Floor Dysfunct. 1996;7(5):242-55. doi: 10.1007/BF01901246.
2
Distribution of xenon-133 in mice from the urinary bladder.氙-133在小鼠膀胱中的分布。
Eur J Nucl Med. 1985;10(7-8):369-72. doi: 10.1007/BF00251315.
3
The reabsorption of creatinine from the rabbit bladder.兔膀胱对肌酐的重吸收
Urol Res. 1975 Dec 30;3(4):183-6. doi: 10.1007/BF00261955.