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双胎与单胎妊娠中超声引导与体格检查引导下的宫颈环扎术

Ultrasound-indicated and physical examination-indicated cervical cerclage in twin versus singleton gestations.

作者信息

Amitai Komem Daphna, Meyer Raanan, Yagel Itai, Shai Daniel, Mashiach Roy, Hendler Israel, Mazaki-Tovi Shali, Yinon Yoav

机构信息

Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer Affiliated to Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

J Obstet Gynaecol Res. 2025 Mar;51(3):e16263. doi: 10.1111/jog.16263.

DOI:10.1111/jog.16263
PMID:40070004
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11897582/
Abstract

AIM

To compare the safety and efficacy of ultrasound- and physical examination-indicated cervical cerclage in twin versus singleton gestations.

METHODS

A retrospective cohort study of all ultrasound-indicated (cervical length ≤ 25 mm) and physical examination-indicated cerclage cases performed over a 9-year period. The primary outcome was the time interval from cerclage placement to delivery.

RESULTS

The study cohort included 94 singleton and 16 twin pregnancies. The time interval from cerclage placement to delivery was comparable in singleton and twin gestations (14.77 vs. 12.07 weeks, p = 0.11), as were the rates of preterm births before 28 and 32 weeks. The rate of alive newborns >24 weeks was lower in the twin group (71.9% vs. 88.3%, p = 0.028). Regression analysis identified that cervical dilation, but not twin gestation, was the only factor independently associated with an increased risk for birth before 32 weeks.

CONCLUSION

Ultrasound-indicated and physical examination-indicated cerclage had comparable efficacy in prolonging pregnancy in twin and singleton gestations, though live birth rates were lower in twins.

摘要

目的

比较超声引导与体格检查引导下宫颈环扎术在双胎妊娠与单胎妊娠中的安全性和有效性。

方法

一项回顾性队列研究,纳入9年期间所有超声引导(宫颈长度≤25mm)和体格检查引导下的宫颈环扎病例。主要结局是从宫颈环扎到分娩的时间间隔。

结果

研究队列包括94例单胎妊娠和16例双胎妊娠。单胎妊娠和双胎妊娠从宫颈环扎到分娩的时间间隔相当(14.77周对12.07周,p = 0.11),28周和32周前的早产率也相当。双胎组24周以上存活新生儿的比例较低(71.9%对88.3%,p = 0.028)。回归分析确定,宫颈扩张而非双胎妊娠是与32周前分娩风险增加独立相关的唯一因素。

结论

超声引导和体格检查引导下的宫颈环扎术在延长双胎妊娠和单胎妊娠的孕周方面疗效相当,尽管双胎的活产率较低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e0c/11897582/efa9218cb82b/JOG-51-0-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e0c/11897582/efa9218cb82b/JOG-51-0-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e0c/11897582/efa9218cb82b/JOG-51-0-g001.jpg

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本文引用的文献

1
Physical examination-indicated cerclage in twin pregnancy: a randomized controlled trial.体格检查指征下的双胎妊娠宫颈环扎术:一项随机对照试验。
Am J Obstet Gynecol. 2020 Dec;223(6):902.e1-902.e11. doi: 10.1016/j.ajog.2020.06.047. Epub 2020 Jun 25.
2
The placement of a cerclage in patients with twin pregnancies and a short cervix is associated with increased risk of preterm birth and adverse perinatal outcome.对于双胎妊娠且宫颈短的患者进行宫颈环扎术与早产风险增加及围产期不良结局相关。
Am J Obstet Gynecol. 2020 Feb;222(2):194-196. doi: 10.1016/j.ajog.2019.09.038. Epub 2019 Oct 3.
3
Twin pregnancies treated with emergency or ultrasound-indicated cerclage to prevent preterm births.
经紧急治疗或超声检查指示行宫颈环扎术以预防早产的双胎妊娠。
J Matern Fetal Neonatal Med. 2020 Oct;33(19):3227-3232. doi: 10.1080/14767058.2019.1570119. Epub 2019 Jan 27.
4
Cerclage for women with twin pregnancies: a systematic review and metaanalysis.双胎妊娠孕妇行环扎术:系统评价和荟萃分析。
Am J Obstet Gynecol. 2019 Jun;220(6):543-557.e1. doi: 10.1016/j.ajog.2018.11.1105. Epub 2018 Dec 7.
5
The impact of cerclage in twin pregnancies on preterm birth rate before 32 weeks.宫颈环扎术对双胎妊娠32周前早产率的影响。
J Matern Fetal Neonatal Med. 2019 Jul;32(13):2143-2151. doi: 10.1080/14767058.2018.1427719. Epub 2018 Jan 23.
6
Outcomes of physical examination-indicated cerclage in twin pregnancies with acute cervical insufficiency compared to singleton pregnancies.与单胎妊娠相比,双胎妊娠合并急性宫颈机能不全时体格检查指征性宫颈环扎术的结局。
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7
Cerclage Use: A Review of 3 National Guidelines.宫颈环扎术的应用:三项国家指南综述
Obstet Gynecol Surv. 2017 Apr;72(4):235-241. doi: 10.1097/OGX.0000000000000422.
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Ultrasound Obstet Gynecol. 2017 Nov;50(5):569-577. doi: 10.1002/uog.17457. Epub 2017 Oct 5.
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J Matern Fetal Neonatal Med. 2016;29(13):2109-13. doi: 10.3109/14767058.2015.1076786. Epub 2015 Sep 15.