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Does the use of pharmacotherapy interact with the effects of psychotherapy? A meta-analytic review.药物治疗的使用是否会影响心理治疗的效果?一项荟萃分析综述。
Eur Psychiatry. 2023 Aug 3;66(1):e63. doi: 10.1192/j.eurpsy.2023.2437.
2
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Ann Gen Psychiatry. 2023 Apr 21;22(1):15. doi: 10.1186/s12991-023-00447-0.
3
Cognitive behavior therapy vs. control conditions, other psychotherapies, pharmacotherapies and combined treatment for depression: a comprehensive meta-analysis including 409 trials with 52,702 patients.认知行为疗法与抑郁症的对照条件、其他心理疗法、药物疗法及联合治疗的比较:一项纳入409项试验、52702例患者的综合荟萃分析
World Psychiatry. 2023 Feb;22(1):105-115. doi: 10.1002/wps.21069.
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Efficacy of short-term psychodynamic psychotherapy (STPP) in depressive disorders: A systematic review and meta-analysis.短期心理动力学心理治疗(STPP)治疗抑郁障碍的疗效:系统评价和荟萃分析。
J Affect Disord. 2023 Mar 15;325:169-176. doi: 10.1016/j.jad.2022.12.161. Epub 2023 Jan 6.
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Response to acute monotherapy for major depressive disorder in randomized, placebo controlled trials submitted to the US Food and Drug Administration: individual participant data analysis.美国食品和药物管理局提交的随机、安慰剂对照试验中治疗重度抑郁症急性单药治疗的反应:个体参与者数据分析。
BMJ. 2022 Aug 2;378:e067606. doi: 10.1136/bmj-2021-067606.
6
Meta-analytic evidence of depression and anxiety in Eastern Europe during the COVID-19 pandemic.新冠疫情期间东欧地区抑郁和焦虑的荟萃分析证据。
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7
Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic.2020 年 COVID-19 大流行期间 204 个国家和地区的抑郁和焦虑障碍的全球患病率和负担。
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8
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9
Initial treatment choices to achieve sustained response in major depression: a systematic review and network meta-analysis.在重度抑郁症中实现持续缓解的初始治疗选择:一项系统评价和网状荟萃分析
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The effects of psychotherapies for depression on response, remission, reliable change, and deterioration: A meta-analysis.抑郁症心理治疗的反应、缓解、可靠变化和恶化效果的荟萃分析。
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抑郁症的药物治疗与心理治疗——互补还是排斥?

Pharmacotherapy and psychotherapy in depression - complementarity or exclusion?

作者信息

Mosiołek Anna, Podlecka Marlena

机构信息

Department of Forensic Psychiatry, Institute of Psychiatry and Neurology in Warsaw, Poland.

Department of Neuroses, Personality Disorders and Eating Disorders, Institute of Psychiatry and Neurology in Warsaw, Poland.

出版信息

Postep Psychiatr Neurol. 2024 Dec;33(4):257-266. doi: 10.5114/ppn.2024.147104. Epub 2025 Feb 25.

DOI:10.5114/ppn.2024.147104
PMID:40070429
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11891753/
Abstract

PURPOSE

This article attempts to outline the dilemma regarding the use of pharmacotherapy and psychotherapy in the treatment of mental disorders with particular emphasis on depression. Depressive disorder is one of the most common mental disorders suffered by society; it affects from 5% to over 12% of the population [1]. It is also a growing problem as the number of diagnoses has increased over the last decades.

VIEWS

The numerous organisations working to improve mental health have constructed guidelines focused on shaping preventive intervention and therapeutic procedures. However, the method of selecting a procedure remains unclear, with the choice between pharmacotherapy and psychotherapy being particularly troublesome. This begs the question of whether these forms of interaction are complementary or exclusive. The article provides an overview of the current discussion on the legitimacy of using multiple forms of interactions when treating depression. Currently, the treatment of depression is based primarily on pharmacotherapy using antidepressants and psychotherapy as well as combined treatment.

CONCLUSIONS

Although a diverse range of psychotherapeutic approaches are used to treat depression, research indicates that all leading approaches are similarly effective. Pharmacotherapy and psychotherapy offer comparable effectiveness in reducing depressive symptoms and demonstrate similar effects on neuronal activity. Combined treatment may offer optimal effectiveness, especially with moderate and severe symptoms of depression.

摘要

目的

本文试图概述在精神障碍治疗中使用药物治疗和心理治疗所面临的困境,尤其着重于抑郁症。抑郁症是社会中最常见的精神障碍之一;它影响着5%至超过12%的人口[1]。随着过去几十年诊断数量的增加,这也是一个日益严重的问题。

观点

众多致力于改善心理健康的组织已经制定了侧重于塑造预防干预和治疗程序的指南。然而,选择程序的方法仍不明确,药物治疗和心理治疗之间的选择尤其棘手。这就引出了一个问题,即这些互动形式是互补的还是相互排斥的。本文概述了当前关于在治疗抑郁症时使用多种互动形式的合理性的讨论。目前,抑郁症的治疗主要基于使用抗抑郁药的药物治疗、心理治疗以及联合治疗。

结论

尽管多种心理治疗方法被用于治疗抑郁症,但研究表明,所有主要方法的效果都相似。药物治疗和心理治疗在减轻抑郁症状方面具有相当的效果,并且对神经元活动表现出相似的影响。联合治疗可能提供最佳效果,尤其是对于中度和重度抑郁症症状。