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重症肺炎合并深静脉血栓形成:一例报告

Severe pneumonia complicated by deep vein thrombosis: a case report.

作者信息

Zhang Anbing, Huang Ting, Lao Xiaoli, Ma Jun, Xia Xiuqiong, Liang Jianping

机构信息

Department of Pulmonary and Critical Care Medicine, Zhongshan People's Hospital, Zhongshan, China.

Shenzhen University Medical School, Shenzhen University, Shenzhen, China.

出版信息

Front Med (Lausanne). 2025 Feb 25;12:1527556. doi: 10.3389/fmed.2025.1527556. eCollection 2025.

DOI:10.3389/fmed.2025.1527556
PMID:40070648
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11893372/
Abstract

Deep vein thrombosis (DVT) of the legs is a rare but clinically important complication of pneumonia. We report a case of a 51-year-old man who was admitted to the hospital with fever, cough, and dyspnea. Next-generation sequencing confirmed the diagnosis of pneumonia. His D-dimer level was elevated on admission, and ultrasound confirmed DVT in the legs. The patient was treated with intravenous doxycycline for the infection and rivaroxaban as an anticoagulant. His condition gradually improved and he was discharged after making a full recovery. In this paper, we explore the potential association between infection and venous thrombosis, as well as clinical management strategies.

摘要

腿部深静脉血栓形成(DVT)是肺炎一种罕见但临床上重要的并发症。我们报告一例51岁男性患者,因发热、咳嗽和呼吸困难入院。下一代测序确诊为肺炎。入院时其D-二聚体水平升高,超声证实腿部存在深静脉血栓。患者接受静脉注射强力霉素治疗感染,并使用利伐沙班作为抗凝剂。其病情逐渐好转,完全康复后出院。在本文中,我们探讨了感染与静脉血栓形成之间的潜在关联以及临床管理策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e52a/11893372/e6235494e6bb/fmed-12-1527556-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e52a/11893372/a163ea6d9a3d/fmed-12-1527556-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e52a/11893372/e6235494e6bb/fmed-12-1527556-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e52a/11893372/a163ea6d9a3d/fmed-12-1527556-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e52a/11893372/e6235494e6bb/fmed-12-1527556-g002.jpg

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本文引用的文献

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Infect Drug Resist. 2023 Nov 6;16:7063-7069. doi: 10.2147/IDR.S435246. eCollection 2023.
2
[Preliminary progress in the study of the relationship between COVID-19 infection and partial arterial or venous diseases].[新型冠状病毒肺炎感染与部分动静脉疾病关系的研究初步进展]
Zhonghua Wai Ke Za Zhi. 2023 Dec 1;61(12):1119-1123. doi: 10.3760/cma.j.cn112139-20230130-00041.
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Risk of venous thromboembolism in patients undergoing gastric cancer surgery: a systematic review and meta-analysis.
接受胃癌手术患者发生静脉血栓栓塞的风险:一项系统评价和荟萃分析。
BMC Cancer. 2023 Oct 3;23(1):933. doi: 10.1186/s12885-023-11424-x.
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Epidemiological and clinical characteristics of psittacosis among cases with complicated or atypical pulmonary infection using metagenomic next-generation sequencing: a multi-center observational study in China.鹦鹉热病例中采用宏基因组下一代测序的复杂或非典型肺部感染的流行病学和临床特征:中国多中心观察性研究。
Ann Clin Microbiol Antimicrob. 2023 Sep 7;22(1):80. doi: 10.1186/s12941-023-00631-w.
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Role of SARS-COV-2 and ACE2 in the pathophysiology of peripheral vascular diseases.SARS-COV-2 和 ACE2 在周围血管疾病病理生理学中的作用。
Biomed Pharmacother. 2023 Oct;166:115321. doi: 10.1016/j.biopha.2023.115321. Epub 2023 Aug 17.
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J Thromb Haemost. 2024 Jan;22(1):7-22. doi: 10.1016/j.jtha.2023.07.020. Epub 2023 Aug 3.
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A retrospective study of the clinical characteristics of 9 children with pulmonary embolism associated with Mycoplasma pneumoniae pneumonia.回顾性分析 9 例肺炎支原体肺炎合并肺血栓栓塞症患儿的临床特征。
BMC Pediatr. 2023 Jul 20;23(1):370. doi: 10.1186/s12887-023-04188-7.
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Infect Drug Resist. 2023 Apr 12;16:2141-2145. doi: 10.2147/IDR.S393256. eCollection 2023.
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