Goni Dit Alassan Maman Bachir, Abdoulaye Zeidou Maiga, Alkassoum Salifou Ibrahim, Mounkaïla Midou Marie, Garba Abdoul Aziz, Doutchi Mahamadou, Harouna Moussa, Ibrahim Mamadou Abdoul Kadir, Adehossi Eric, Aka Joseph, Mamadou Saïdou
Département de santé publique, Université André Salifou, Faculté des sciences de la santé (FSS), Hôpital national, BP 656, Zinder, Niger.
Département de santé publique, Université Abdou Moumouni, FSS, Hôpital national, BP 10896, Niamey, Niger.
Med Trop Sante Int. 2024 Oct 30;4(4). doi: 10.48327/mtsi.v4i4.2024.449. eCollection 2024 Dec 31.
Acute flaccid paralysis (AFP) caused by acute anterior poliomyelitis (AAP) remains endemic in some Asian and African countries, particularly Niger. Performance indicators defined by the WHO are used to evaluate the AFP surveillance system in affected countries. The objective of this study is to assess its outcomes in Niger from 1998 to 2021. The objective of this study is to assess its outcomes in Niger from 1998 to 2021.
This is a cross-sectional study based on all secondary data from AFP case surveillance reported to the Directorate of Surveillance and Epidemic Response in Niger, over a 24-year period from 1998 to 2021.
The sample included 9,659 patients of all ages and sexes. The sex ratio was 1.23, and 92.01% of patients were under 5 years old. The Maradi region ranked first among Niger's eight regions in terms of reported cases (32.27%). It hosts a large portion of the population from neighboring Nigeria, a country also endemic for AFP. More than half of the patients (66.59%) had received 1 to 10 doses of oral polio vaccine. From 1998 to 2021, 8,419 stool samples from 9,494 cases (88.70%) were usable upon arrival at the laboratory. Confirmed and compatible poliovirus cases accounted for 0.80% and 2.35%, respectively. Of the 276 patients who presented with paralysis, 71.73% suffered from paralysis in both limbs, and in 94.35% of the cases, the paralysis had progressed within 3 days.
This study allowed for an analysis of the performance of the active AFP surveillance system. In Niger, this surveillance is acceptable according to performance indicators, but there is still much progress to be made at both the population level and within the healthcare workforce.
急性前髓灰质炎（AAP）所致的急性弛缓性麻痹（AFP）在一些亚洲和非洲国家，尤其是尼日尔，仍然呈地方性流行。世界卫生组织定义的绩效指标用于评估受影响国家的AFP监测系统。本研究的目的是评估1998年至2021年期间该系统在尼日尔的成果。本研究的目的是评估1998年至2021年期间该系统在尼日尔的成果。
这是一项横断面研究，基于1998年至2021年这24年间向尼日尔监测与疫情应对局报告的AFP病例监测的所有二级数据。
样本包括9659名各年龄和性别的患者。性别比为1.23，92.01%的患者年龄在5岁以下。在报告病例方面，马拉迪地区在尼日尔的八个地区中排名第一（32.27%）。该地区有很大一部分来自邻国尼日利亚的人口，而尼日利亚也是AFP的地方性流行国家。超过一半的患者（66.59%）接种过1至10剂口服脊髓灰质炎疫苗。从1998年到2021年，9494例病例中的8419份粪便样本（88.70%）在抵达实验室时可供检测。确诊的脊髓灰质炎病毒病例和可能的脊髓灰质炎病毒病例分别占0.80%和2.35%。在出现麻痹症状的276名患者中，71.73%的患者双下肢麻痹，94.35%的病例中，麻痹症状在3天内进展。
本研究对主动AFP监测系统的绩效进行了分析。在尼日尔，根据绩效指标，这种监测是可以接受的，但在人群层面和医疗保健工作人员内部仍有很大的改进空间。
