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富血小板血浆注射与不注射情况下双侧耳垂裂修复的比较评估——体内随机研究

Comparative Evaluation of Bilateral Earlobe Cleft Repair with and Without Platelet Rich Plasma Injection- In vivo Randomized Study.

作者信息

Talele Priti, Shetty Lakshmi, Raut Shreya Jeetendra, Kulkarni Vishal, Singh Akhilesh Kumar, Mishra Madan, Anandkumar Janani

机构信息

Department of Oral and Maxillofacial Surgery, Dr. D.Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune, 411018 India.

Department of Oral and Maxillofacial Surgery, Command Military Dental Centre, Lucknow, Uttar Pradesh 226002 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2025 Jan;77(1):242-249. doi: 10.1007/s12070-024-05158-w. Epub 2024 Nov 11.

DOI:10.1007/s12070-024-05158-w
PMID:40071003
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11890899/
Abstract

UNLABELLED

Earlobe clefts have been the major concern for aesthetic repair in the present situation. The advent of platelet-rich plasma (PRP) for enhancement of healing has never been treated for cleft earlobe repair. This study aims to compare and evaluate the efficacy of wound healing with and without platelet-rich plasma injection in bilateral earlobe cleft lobe repair. 50 patients presenting bilateral earlobe cleft were selected for this study. Earlobe repair (cross-stitch technique) was performed under local anaesthesia using 5-0 prolene sutures. On one side platelet-rich plasma was injected intra-dermally. Patient was followed up after 24 h, 8 and 15 days post-operatively for evaluation of pain and scar respectively. Statistically significant/highly significant difference seen for the values between the groups ( < 0.01, 0.05) with higher values at 8 days for group without PRP while lower values for the group with PRP, at 15 days higher values of Stony Brook Scar Evaluation Scale (SBSES) was seen for group with PRP, while lower values for the group without PRP. ELC repair using cross-stitch technique and intradermal PRP injection intra-operatively is a simple, cost effective method and gives good aesthetic results. It also promotes the healing and reduces the chances of scar formation. Length, contour and integrity of the earlobe is also maintained by this technique and this research for the first time in literature proves that such a large sample has been found effective in ELC repair with PRP.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1007/s12070-024-05158-w.

摘要

未标注

在当前情况下,耳垂裂一直是美学修复的主要关注点。富含血小板血浆(PRP)用于促进愈合的方法从未用于耳垂裂修复。本研究旨在比较和评估在双侧耳垂裂修复中注射和不注射富含血小板血浆时伤口愈合的效果。本研究选取了50例双侧耳垂裂患者。使用5-0普理灵缝线在局部麻醉下进行耳垂修复(十字绣技术)。在一侧皮内注射富含血小板血浆。术后24小时、8天和15天对患者进行随访,分别评估疼痛和瘢痕情况。两组之间的值存在统计学显著/高度显著差异(<0.01,0.05),未注射PRP组在第8天的值较高,而注射PRP组的值较低;在第15天,注射PRP组的石溪瘢痕评估量表(SBSES)值较高,而未注射PRP组的值较低。术中使用十字绣技术和皮内注射PRP进行耳垂裂修复是一种简单、经济有效的方法,能取得良好的美学效果。它还能促进愈合并减少瘢痕形成的机会。该技术还能保持耳垂的长度、轮廓和完整性,并且本研究在文献中首次证明如此大的样本在使用PRP进行耳垂裂修复中是有效的。

补充信息

在线版本包含可在10.1007/s12070-024-05158-w获取的补充材料。

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本文引用的文献

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Platelet-rich plasma, the ultimate secret for youthful skin elixir and hair growth triggering.富含血小板的血浆,青春美肌和促进头发生长的终极秘诀。
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