Redman Ishtar, Sugand Kapil, Daruwalla Aashtad, Clark Andrew
EFORT Open Rev. 2025 Mar 3;10(3):166-171. doi: 10.1530/EOR-2024-0074. Print 2025 Mar 1.
The pre-operative management of fracture blisters is an area of uncertainty within trauma and orthopaedic surgeries. Management strategies vary significantly between and within orthopaedic departments across the United Kingdom. The purpose of this systematic review was to comprehensively appraise and synthesize the existing literature pertaining to this topic, highlighting current practices and areas for ongoing research.
Extensive electronic literature searches were performed on PubMed/MEDLINE (January 1946-May 2024), Embase (January 1974-May 2024) and Cochrane library (January 1933-May 2024) databases. The search terms were as follows: (fracture blister OR bone blister*) AND (dress* OR drain* OR aspirat* OR deroof* OR manage*). These keywords were searched in the subject headings, in title and in abstract.
The results of the search methodology revealed five articles, which represented the best evidence to the clinical question. These papers reported on rates of wound healing and post-operative infection, time to surgical readiness and treatment costs, following varying treatment modalities in 1162 patients. The authors, publication dates, countries, patient groups, study outcomes and results of these papers are tabulated in Supplementary Table 1.
Fracture blisters pose a significant challenge in clinical practice, leading to delays in surgery, suboptimal surgical approaches and complications in wound healing post-operatively. Currently, there is no consensus describing the optimal management of these blisters. This review challenges the conventional belief that fracture blisters are sterile, highlighting that the application of topical agents to the deroofed blister bed may expedite surgical readiness.
骨折水疱的术前管理是创伤和骨科手术中一个存在不确定性的领域。英国各骨科科室之间以及科室内部的管理策略差异很大。本系统评价的目的是全面评估和综合有关该主题的现有文献,突出当前的实践情况和有待进一步研究的领域。
在PubMed/MEDLINE(1946年1月至2024年5月)、Embase(1974年1月至2024年5月)和Cochrane图书馆(1933年1月至2024年5月)数据库中进行了广泛的电子文献检索。检索词如下:(骨折水疱或骨水疱*)以及(敷料或引流或抽吸或去除顶皮或管理*)。这些关键词在主题词、标题和摘要中进行检索。
检索方法的结果显示有五篇文章,它们代表了对该临床问题的最佳证据。这些论文报告了1162例患者在采用不同治疗方式后的伤口愈合率和术后感染情况、手术准备时间以及治疗费用。这些论文的作者、发表日期、国家、患者群体、研究结果列于补充表1中。
骨折水疱在临床实践中构成了重大挑战,导致手术延迟、手术方式欠佳以及术后伤口愈合并发症。目前,对于这些水疱的最佳管理尚无共识。本综述对骨折水疱无菌的传统观念提出了质疑,强调在去除顶皮的水疱创面上应用局部用药可能会加快手术准备进程。