Peršić Bukmir Romana, Paljević Ema, Vidas Hrstić Jelena, Božac Elvis, Mocny-Pachonska Katarzyna, Brekalo Pršo Ivana
Department of Endodontics and Restorative Dentistry, Faculty of Dental Medicine, University of Rijeka, Rijeka, Croatia.
Division of Dentistry, Department of Conservative Dentistry with Endodontics, School of Medicine, Medical University of Silesia in Katowice, Bytom, Poland.
Eur J Dent. 2025 Jul;19(3):793-800. doi: 10.1055/s-0044-1800825. Epub 2025 Mar 12.
The present study aimed to compare dental, endodontic, and periodontal status in patients with Hashimoto's disease and healthy patients, as well as to disclose the relation between dental variables and Hashimoto's disease.
The research included 85 patients affected by Hashimoto's thyroiditis (analyzed group) and 85 healthy patients (control group). The two groups were matched according to age and gender. Data regarding patients' health status was acquired from their medical records. Data regarding dental, endodontic, and periodontal status were acquired from patients' dental records and digital panoramic radiographs.
Since a nonnormal distribution of data was detected, a median and interquartile range were used as a measure of central tendency and dispersion. Mann-Whitney test and chi-squared test were used to test the differences between the groups. Multiple linear regression analysis and logistic regression analysis were used to test the association of the data.
Healthy participants had significantly higher median number of teeth with secondary caries (median 2; interquartile range 1-3) when compared with participants with Hashimoto's disease (median 1; interquartile range 0-2; < 0.001). Periodontal disease was present in significantly more participants with Hashimoto's disease than healthy patients (68.2% vs. 45.9%; chi-square = 7.779; = 0.005). The presence of Hashimoto's disease increased the risk of periodontal disease presence three times (odds ratio [OR] = 3.14; 95% confidence interval [CI] 1.38-7.15; = 0.007). The presence of periodontal disease increased the risk of Hashimoto's disease presence by 2.5 times (OR 2.54; 95% CI: 1.36-4.73; = 0.004).
With the study limitations in mind, it may be concluded that a positive relationship between periodontal disease and Hashimoto's thyroiditis exists.
本研究旨在比较桥本氏病患者与健康患者的牙齿、牙髓和牙周状况，并揭示牙齿变量与桥本氏病之间的关系。
该研究纳入了85例桥本氏甲状腺炎患者（分析组）和85例健康患者（对照组）。两组根据年龄和性别进行匹配。患者健康状况的数据从其病历中获取。牙齿、牙髓和牙周状况的数据从患者的牙科记录和数字化全景X线片中获取。
由于检测到数据呈非正态分布，因此使用中位数和四分位数间距作为集中趋势和离散程度的度量。采用曼-惠特尼检验和卡方检验来检验组间差异。使用多元线性回归分析和逻辑回归分析来检验数据的关联性。
与桥本氏病患者相比，健康参与者继发龋的牙齿中位数显著更高（中位数为2；四分位数间距为1 - 3），而桥本氏病患者的中位数为1；四分位数间距为0 - 2；P < 0.001）。患有桥本氏病的参与者患牙周病的比例明显高于健康患者（68.2%对45.9%；卡方 = 7.779；P = 0.005）。患桥本氏病会使患牙周病的风险增加三倍（优势比[OR] = 3.14；95%置信区间[CI] 1.38 - 7.15；P = 0.007）。患牙周病会使患桥本氏病的风险增加2.5倍（OR 2.54；95% CI：1.36 - 4.73；P = 0.004）。
考虑到研究的局限性，可以得出结论，牙周病与桥本氏甲状腺炎之间存在正相关关系。
