Solderer A, Giuliani C, Wiedemeier D B, Jung R E, Schmidlin P R
Clinic of Conservative and Preventive Dentistry, Division for Periodontology and Peri-Implant Diseases, Center for Dental Medicine, University of Zurich, Zurich, Switzerland.
Statistics Group, Center for Dental Medicine, University of Zurich, Zurich, Switzerland.
Int J Implant Dent. 2025 Mar 12;11(1):20. doi: 10.1186/s40729-025-00613-x.
To retrospectively assess the potential impact of biological and host factors on radiographic bone loss following tissue-level implant placement and prosthetic rehabilitation.
The University database was reviewed to identify patients treated with tissue-level implants between 2006 and 2020 at the University of Zurich, Switzerland. The study included patients who received screw-retained implant rehabilitations in the posterior area without simultaneous hard- or soft-tissue augmentations and had a follow-up period of at least 12 months. Radiographic measures of marginal bone loss and supracrestal tissue height were conducted using periapical x-rays at different time points. Additional factors analysed included age, gender, smoking status, history of periodontitis, jaw of treatment, type of reconstruction, and prosthetic emergence angle. Associations between marginal bone loss and potential explanatory variables were visualised and analysed. Elastic net regressions were applied to examine potential relationships with marginal bone loss.
A total of 1,479 patients were treated with tissue-level implants. After applying inclusion and exclusion criteria, 106 patients with 106 implants were included in the statistical evaluation after one year (T1, n = 106 implants), and 59 patients with 59 implants were evaluated after three years (T2, n = 59 implants). The mean marginal bone loss was 0.93 mm (SD 0.83) at T1 and 1.04 mm (SD 0.97) at T2. A strong correlation (Spearman) was found between mesial and distal bone loss. Smoking status and the jaw undergoing treatment were associated with bone loss. While these associations were observed in the univariate analysis, a more comprehensive multivariate analysis revealed that these variables had a limited effect on explaining radiographic bone loss.
During the initial rehabilitation period in tissue-level implants in this cohort smoking status and jaw of treatment seemed to influence early peri-implant bone loss. Further, a strong correlation between mesial and distal MBL was observed. Additional research is required to determine factors contributing to early bone loss following implant-prosthetic rehabilitation.
回顾性评估生物学和宿主因素对组织水平种植体植入及修复后影像学骨吸收的潜在影响。
检索瑞士苏黎世大学数据库，以确定2006年至2020年间接受组织水平种植体治疗的患者。该研究纳入了在后部区域接受螺钉固位种植体修复且未同时进行硬组织或软组织增量手术、随访期至少12个月的患者。在不同时间点使用根尖片测量边缘骨吸收和龈上组织高度。分析的其他因素包括年龄、性别、吸烟状况、牙周炎病史、治疗部位、修复类型和修复体龈缘角度。对边缘骨吸收与潜在解释变量之间的关联进行可视化和分析。应用弹性网回归分析来检验与边缘骨吸收的潜在关系。
共有1479例患者接受了组织水平种植体治疗。应用纳入和排除标准后，106例患者的106枚种植体在1年后纳入统计评估（T1，n = 106枚种植体），59例患者的59枚种植体在3年后进行评估（T2，n = 59枚种植体）。T1时平均边缘骨吸收为0.93mm（标准差0.83），T2时为1.04mm（标准差0.97）。发现近中骨吸收和远中骨吸收之间存在强相关性（Spearman）。吸烟状况和治疗部位与骨吸收有关。虽然在单因素分析中观察到了这些关联，但更全面的多因素分析显示，这些变量对解释影像学骨吸收的作用有限。
在该队列中组织水平种植体的初始修复期，吸烟状况和治疗部位似乎会影响种植体周围早期骨吸收。此外，观察到近中与远中边缘骨吸收之间存在强相关性。需要进一步研究以确定种植体修复后早期骨吸收的相关因素。
