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本文引用的文献

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Incidence of HIV and hepatitis C virus among people who inject drugs, and associations with age and sex or gender: a global systematic review and meta-analysis.注射吸毒人群中 HIV 和丙型肝炎病毒的感染率,以及与年龄、性别或性别认同的相关性:一项全球系统评价和荟萃分析。
Lancet Gastroenterol Hepatol. 2023 Jun;8(6):533-552. doi: 10.1016/S2468-1253(23)00018-3. Epub 2023 Mar 27.
2
Hepatitis C Virus Elimination by 2030: Conquering Mount Improbable.到2030年消除丙型肝炎病毒:攻克“不可能之峰”。
Clin Liver Dis (Hoboken). 2021 Jan 13;16(6):254-261. doi: 10.1002/cld.978. eCollection 2020 Dec.
3
Prevention of Hepatitis A Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices, 2020.美国甲型肝炎病毒感染预防:免疫实践咨询委员会建议,2020 年。
MMWR Recomm Rep. 2020 Jul 3;69(5):1-38. doi: 10.15585/mmwr.rr6905a1.
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CDC Recommendations for Hepatitis C Screening Among Adults - United States, 2020.美国疾病预防控制中心关于 2020 年成年人丙型肝炎筛查的建议。
MMWR Recomm Rep. 2020 Apr 10;69(2):1-17. doi: 10.15585/mmwr.rr6902a1.
5
Needle syringe programmes and opioid substitution therapy for preventing hepatitis C transmission in people who inject drugs.针具交换计划和阿片类药物替代疗法预防注射吸毒者丙型肝炎传播
Cochrane Database Syst Rev. 2017 Sep 18;9(9):CD012021. doi: 10.1002/14651858.CD012021.pub2.
6
Effectiveness of needle and syringe Programmes in people who inject drugs - An overview of systematic reviews.注射吸毒者中针头和注射器计划的有效性——系统评价概述
BMC Public Health. 2017 Apr 11;17(1):309. doi: 10.1186/s12889-017-4210-2.
7
Patient choice in opt-in, active choice, and opt-out HIV screening: randomized clinical trial.选择加入、主动选择和选择退出的HIV筛查中的患者选择:随机临床试验。
BMJ. 2016 Jan 19;532:h6895. doi: 10.1136/bmj.h6895.
8
Routine opt-out HIV screening: more evidence in support of alternative approaches?常规退出式HIV筛查:是否有更多证据支持替代方法?
Sex Transm Dis. 2014 Jun;41(6):403-6. doi: 10.1097/OLQ.0000000000000139.
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Effect of risk-reduction counseling with rapid HIV testing on risk of acquiring sexually transmitted infections: the AWARE randomized clinical trial.风险降低咨询联合快速 HIV 检测对性传播感染风险的影响:AWARE 随机临床试验。
JAMA. 2013 Oct 23;310(16):1701-10. doi: 10.1001/jama.2013.280034.
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Opt-out testing for stigmatized diseases: a social psychological approach to understanding the potential effect of recommendations for routine HIV testing.规避检测污名化疾病:理解常规 HIV 检测建议潜在影响的社会心理学方法。
Health Psychol. 2009 Nov;28(6):675-81. doi: 10.1037/a0016395.

佛罗里达州一个注射器服务项目中的匿名退出式艾滋病毒和丙型肝炎筛查。

Anonymous Opt-Out HIV and hepatitis C screening at a syringe services program in Florida.

作者信息

Henderson Heather, Wilson Jason, McCoy Bernice, Sarmento Megan, Oxner Asa

机构信息

Department of Emergency Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL, 33612, USA.

Tampa General Hospital, Tampa, FL, 33606, USA.

出版信息

Harm Reduct J. 2025 Mar 12;22(1):30. doi: 10.1186/s12954-025-01182-3.

DOI:10.1186/s12954-025-01182-3
PMID:40075495
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11899791/
Abstract

This paper outlines the implementation of opt-out HIV and Hepatitis C (HCV) screening at a syringe services program (SSP) in Florida, highlighting its effectiveness in reducing the transmission of these infectious diseases. Historically, many SSPs have utilized opt-in testing models, which require participants to actively choose testing and often result in low participation rates. Recognizing the need for a more effective approach and to comply with Florida's regulatory requirements under the Infectious Disease Elimination Act, we transitioned to an opt-out testing model at our SSP. This model integrates routine, anonymous, and voluntary testing into standard care, normalizing the process and reducing stigma associated with infectious disease screening. Initially, our policy tied testing to access to specific services, including syringe exchange, to meet compliance with Florida Department of Health mandates. However, after feedback from participants, staff, and community members, we revised our approach to allow all participants to access all services, regardless of their decision to participate in testing. Importantly, this policy change did not decrease testing rates, with only 6 out of 226 new enrollments (3%) opting out since the implementation of opt-out screening. By fostering a trusting, non-coercive environment and normalizing screening as part of routine care, we achieved high rates of participation while maintaining participant autonomy. Since transitioning to an opt-out model, we have conducted nearly 3,000 HIV and HCV tests, with seropositivity rates of 3.8% and 54%, respectively. These efforts have facilitated early detection, rapid linkage to care, and reduced transmission within the community. Our findings underscore the importance of comprehensive, repeat testing in high-risk populations and demonstrate the potential for opt-out models to serve as a scalable framework for SSPs nationwide. This approach not only fulfills regulatory and public health objectives but also strengthens the role of SSPs as critical interventions in combating HIV and HCV transmission.

摘要

本文概述了佛罗里达州一个注射器服务项目(SSP)实施的艾滋病病毒(HIV)和丙型肝炎病毒(HCV)主动退出式筛查,强调了其在减少这些传染病传播方面的有效性。从历史上看,许多注射器服务项目采用的是主动参与式检测模式,即要求参与者主动选择检测,这往往导致参与率较低。认识到需要一种更有效的方法,并为了遵守佛罗里达州《传染病消除法》的监管要求,我们在我们的注射器服务项目中过渡到了主动退出式检测模式。这种模式将常规、匿名和自愿检测纳入标准护理,使这一过程常态化,并减少与传染病筛查相关的污名化。最初,我们的政策将检测与获得特定服务(包括注射器交换)挂钩,以符合佛罗里达州卫生部的规定。然而,在收到参与者、工作人员和社区成员的反馈后,我们修改了方法,允许所有参与者获得所有服务,无论他们是否决定参与检测。重要的是,这一政策变化并没有降低检测率,自实施主动退出式筛查以来,226名新登记参与者中只有6人(3%)选择退出。通过营造一个信任、非强制性的环境,并将筛查作为常规护理的一部分使其常态化,我们在保持参与者自主性的同时实现了高参与率。自过渡到主动退出式模式以来,我们已经进行了近3000次HIV和HCV检测,血清阳性率分别为3.8%和54%。这些努力促进了早期发现、快速连接到治疗,并减少了社区内的传播。我们的研究结果强调了在高危人群中进行全面、重复检测的重要性,并证明了主动退出式模式作为全国注射器服务项目可扩展框架的潜力。这种方法不仅实现了监管和公共卫生目标,还加强了注射器服务项目作为抗击HIV和HCV传播关键干预措施的作用。