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与草食家畜环境适应性相关的潜在遗传标记

Potential Genetic Markers Associated with Environmental Adaptability in Herbivorous Livestock.

作者信息

Liu Xiaotong, Peng Yongdong, Zhang Xinhao, Chen Wenting, Chen Yinghui, Wei Lin, Zhu Qifei, Khan Muhammad Zahoor, Wang Changfa

机构信息

Liaocheng Research Institute of Donkey High-Efficiency Breeding and Ecological Feeding, College of Agriculture and Biology, Liaocheng University, Liaocheng 252000, China.

出版信息

Animals (Basel). 2025 Mar 5;15(5):748. doi: 10.3390/ani15050748.

DOI:10.3390/ani15050748
PMID:40076029
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11898825/
Abstract

Herbivorous livestock, such as cattle, sheep, goats, horses, and donkeys, play a crucial role in agricultural production and possess remarkable resilience to extreme environmental conditions, driven by complex genetic mechanisms. Recent advancements in high-throughput sequencing, genome assembly, and environmental data integration have enabled a deeper understanding of the genetic basis of their environmental adaptation. This review identifies key genes associated with high-altitude, heat, cold, and drought adaptation, providing insights into the molecular mechanisms underlying these traits. By elucidating these genetic adaptations, our study aims to support conservation efforts, inform selective breeding programs, and enhance agricultural productivity, ultimately contributing to sustainable livestock farming and economic benefits for farmers.

摘要

食草家畜,如牛、羊、山羊、马和驴,在农业生产中发挥着关键作用,并通过复杂的遗传机制对极端环境条件具有显著的适应能力。高通量测序、基因组组装和环境数据整合方面的最新进展,使人们能够更深入地了解它们环境适应的遗传基础。本综述确定了与高海拔、高温、低温和干旱适应相关的关键基因,为这些性状的分子机制提供了见解。通过阐明这些遗传适应性,我们的研究旨在支持保护工作,为选择性育种计划提供信息,并提高农业生产力,最终为可持续畜牧业和农民的经济效益做出贡献。

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本文引用的文献

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BioTech (Basel). 2024 Nov 15;13(4):49. doi: 10.3390/biotech13040049.
2
Whole genome re-sequencing reveals high altitude adaptation signatures and admixture in Ladakhi cattle.全基因组重测序揭示了拉达克牛的高原适应特征和杂交。
Gene. 2025 Jan 15;933:148957. doi: 10.1016/j.gene.2024.148957. Epub 2024 Sep 19.
3
Multi-omic Analyses Shed Light on The Genetic Control of High-altitude Adaptation in Sheep.多组学分析揭示了绵羊高原适应的遗传控制。
Genomics Proteomics Bioinformatics. 2024 Jul 3;22(2). doi: 10.1093/gpbjnl/qzae030.
4
Genomic insights into adaptation and inbreeding among Sub-Saharan African cattle from pastoral and agropastoral systems.对撒哈拉以南非洲畜牧和农牧混合系统中牛的适应性和近亲繁殖的基因组学洞察。
Front Genet. 2024 Jul 25;15:1430291. doi: 10.3389/fgene.2024.1430291. eCollection 2024.
5
Population structure and selection signal analysis of indigenous sheep from the southern edge of the Taklamakan Desert.塔克拉玛干沙漠南缘地方绵羊群体结构和选择信号分析。
BMC Genomics. 2024 Jul 9;25(1):681. doi: 10.1186/s12864-024-10581-y.
6
Recent selection and introgression facilitated high-altitude adaptation in cattle.最近的选择和基因渗入促进了牛类对高海拔的适应。
Sci Bull (Beijing). 2024 Nov 15;69(21):3415-3424. doi: 10.1016/j.scib.2024.05.030. Epub 2024 May 25.
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Sci Rep. 2024 Jun 28;14(1):14908. doi: 10.1038/s41598-024-65303-x.
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