Mor-Josef S, Anteby S O, Schenker J G
Gynecol Oncol. 1985 Jul;21(3):287-93. doi: 10.1016/0090-8258(85)90265-3.
Data of an epidemiologic study of ovarian cancer in Israel are presented. During the 5-year period of this survey, 1001 new cases of primary cancer of the ovary were diagnosed. The findings are compared with those of two previous surveys covering the periods 1960-1965 (746 cases) and 1966-1971 (911 cases). The incidence during the 17-year period ranged between 15 and 19/100,000 women over the age of 15. The disease was three to five times more prevalent in women of European/American origin than in those of Asian/African descent. Seventy-five percent of the patients were between the ages of 45 and 74. The majority (50-71%) were already in stage III or stage IV at diagnosis. Factors affecting the prognosis are the age of the patient and clinical stage of the malignancy when first diagnosed, histology of the tumor, and type of treatment. Although the time interval between onset of the disease and its detection has remained protracted, the 5-year survival rate was improved from 15% during the period 1960-1965 to 31% between the years 1972-1976. This favorable trend is to be ascribed to new treatment modalities.
本文呈现了以色列卵巢癌流行病学研究的数据。在本次调查的5年期间，共诊断出1001例原发性卵巢癌新病例。研究结果与之前两次调查的结果进行了比较，前两次调查分别涵盖1960 - 1965年（746例）和1966 - 1971年（911例）。在这17年期间，15岁以上女性的发病率在每10万人中为15至19例。欧洲/美洲裔女性的发病率是亚洲/非洲裔女性的三到五倍。75%的患者年龄在45至74岁之间。大多数患者（50 - 71%）在确诊时已处于III期或IV期。影响预后的因素包括患者年龄、首次诊断时恶性肿瘤的临床分期、肿瘤组织学类型以及治疗方式。尽管从疾病发作到发现的时间间隔仍然很长，但5年生存率已从1960 - 1965年期间的15%提高到1972 - 1976年期间的31%。这一良好趋势归因于新的治疗方式。
