Hemsworth Jake, Vinogradov Andrej, Lewis William, Woodward Simon, Willcox Darren
Department of Chemistry, University of Manchester, Manchester M13 9PL, UK.
School of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Molecules. 2025 Feb 20;30(5):986. doi: 10.3390/molecules30050986.
A simple one-pot reaction of LiAlH, AlCl, and a secondary amine HNR [R = Et, Pr, Bu, cyclo-CH, (CH), and (CH)] in hydrocarbon solvents results in the formation of exogenous Lewis-base-free amidoalanes [HAl(NR)] (n = 2 or 3) as crystalline solids (35-85% yield). In the solid state (seven X-ray structures), all the amidoalanes exist as dimers, with the exception of the pyrrolidine-derived alane which exists as a trimer. As solids, these amidoalanes exhibit significant kinetic stability towards oxygen/moisture allowing the brief (ca. 5 min.) handling of [HAl(NPr)] in air.
在烃类溶剂中，氢化铝锂、氯化铝与仲胺HNR[R = 乙基、丙基、丁基、环戊基、(CH₂)₅和(CH₂)₆]进行简单的一锅反应，可生成无外源路易斯碱的酰胺铝烷[HAl(NR)₂]（n = 2或3）晶体（产率35 - 85%）。在固态下（七种X射线结构），除了由吡咯烷衍生的铝烷以三聚体形式存在外，所有酰胺铝烷均以二聚体形式存在。作为固体，这些酰胺铝烷对氧气/水分表现出显著的动力学稳定性，使得[HAl(NPr)₂]能够在空气中短暂（约5分钟）处理。
