Martini A K
Handchir Mikrochir Plast Chir. 1985 May;17(3):134-8.
Wedge-like preparations from the palm in Dupuytren's disease in many stages are investigated histologically and with scanning electron microscopy. The preparations comprise the entire soft tissue covering (skin, fat and aponeurosis). The scanning electron microscope enables a three dimensional examination of the surface of the collagen fibers. The following results were obtained: In the region of the skin contraction or the node: There is a displacement and atrophy of the fat layers by the proliferated and thickened connective tissue. The transitions between the various layers are obliterated. The collagen fibers perpendicular to the skin show massive cross-linking and thickening. The pathologically altered aponeurosis shows a variable morphology: the collagen bundles display major variations in diameter and structure. Typing of the disease stage and the morphological alterations is not possible.
对处于多个阶段的掌腱膜挛缩症患者手掌的楔形组织样本进行了组织学和扫描电子显微镜检查。这些样本包括整个软组织覆盖层（皮肤、脂肪和腱膜）。扫描电子显微镜能够对胶原纤维表面进行三维检查。获得了以下结果：在皮肤挛缩或结节区域：增生和增厚的结缔组织使脂肪层发生移位和萎缩。各层之间的过渡消失。垂直于皮肤的胶原纤维出现大量交联和增厚。病理改变的腱膜呈现出不同的形态：胶原束在直径和结构上有很大差异。无法对疾病阶段和形态学改变进行分型。
