Berger A, Gurr E
Handchir Mikrochir Plast Chir. 1985 May;17(3):139-42.
A two-year old boy suffered a contracture of the second and third digit beginning at the age of seven months. The clinical examination suggested a diagnosis of early Dupuytren's disease. A partial fasciectomy was performed. Histological examination showed a fibrosis palmaris similar to Dupuytren's disease. The biochemical examination (Glycans, hyaluronic acid, chrondroitinsulfat, dermatansulfat and heparansulfat) showed also changes in the extracellular proteoglycanmatrix similar to those found in adult Dupuytren's disease.
一名两岁男孩自七个月大时开始出现第二和第三指挛缩。临床检查提示早期杜普伊特伦病的诊断。实施了部分筋膜切除术。组织学检查显示为与杜普伊特伦病相似的掌部纤维化。生化检查（聚糖、透明质酸、硫酸软骨素、硫酸皮肤素和硫酸乙酰肝素）也显示细胞外蛋白聚糖基质存在与成人杜普伊特伦病中所见相似的变化。
