Krystkiewicz Marika, Soyka Michael
Fachklinik Eußerthal, Klinikstr. 1, 76857 Eußerthal, Germany.
Psychiatric Hospital, University of Munich, Nußbaumstr. 7, 80336 Munich, Germany.
Healthcare (Basel). 2025 Feb 28;13(5):535. doi: 10.3390/healthcare13050535.
Individuals with substance use disorders are at risk of displaying suicidal behavior with suicide occurring more frequently compared to the general population. This article gives an overview of the existing literature on the association of substance use disorders, especially alcohol use disorder (AUD), with suicidal behavior. Studies indicate that individuals with AUD report a lifetime prevalence of 40% for at least one instance of attempted suicide. They also have a 10 to 14 times higher risk of suicidal behavior compared to the general population. The protocol and preliminary data from an ongoing study focused on the prevalence and clinical correlations of suicidal ideation and attempts in treatment-seeking inpatients with AUD are presented. The objective of this study is to address open questions regarding the clinical factors and psychiatric comorbidities associated with suicidality in patients with AUD. In a pilot and feasibility study in an inpatient rehabilitation facility for the treatment of substance use disorders, 150 patients with AUD were examined. For assessment, the Beck Depression Inventory (BDI-II), the Symptom Check-list-90 (SCL-90), and the Scale Suicidal Experience and Behavior (SSEV) were used as standardized questionnaires. In addition, psychosocial and sociodemographic variables were recorded. A total of 257 items were surveyed for each respondent. The statistical analysis was carried out using IBM SPSS. The initial evaluation indicates the feasibility of the study with a high number of responders (90% response rate). Of the participants surveyed, 50.7% (N = 76) were at risk of suicide and 40.7% (N = 61) had already made at least one suicide attempt. Even with a small sample size, a significant, moderate-to-large correlation between alcohol use disorder and suicidality could be demonstrated. This confirms that suicidality is a risk factor for patients with AUD. The role of psychiatric comorbidity, clinical correlations and consequences of AUD, Gender and treatment outcome will be studied in a larger sample of 700 patients.
患有物质使用障碍的个体有表现出自杀行为的风险，与普通人群相比，自杀行为更为频繁。本文概述了关于物质使用障碍，尤其是酒精使用障碍（AUD）与自杀行为之间关联的现有文献。研究表明，患有AUD的个体报告至少有一次自杀未遂的终生患病率为40%。与普通人群相比，他们自杀行为的风险也高10至14倍。本文还介绍了一项正在进行的研究的方案和初步数据，该研究聚焦于寻求治疗的AUD住院患者中自杀意念和自杀未遂的患病率及临床相关性。本研究的目的是解决关于AUD患者自杀相关临床因素和精神共病的开放性问题。在一家治疗物质使用障碍的住院康复机构进行的一项试点和可行性研究中，对150名AUD患者进行了检查。评估时，使用贝克抑郁量表（BDI-II）、症状自评量表90（SCL-90）和自杀经历与行为量表（SSEV）作为标准化问卷。此外，还记录了心理社会和社会人口学变量。每位受访者共调查了257个项目。使用IBM SPSS进行统计分析。初步评估表明该研究具有可行性，应答者数量众多（应答率为90%）。在接受调查的参与者中，50.7%（N = 76）有自杀风险，40.7%（N = 61）至少有过一次自杀未遂。即使样本量较小，也能证明酒精使用障碍与自杀倾向之间存在显著的中等到较大的相关性。这证实了自杀倾向是AUD患者的一个风险因素。将在700名患者的更大样本中研究精神共病的作用、AUD的临床相关性和后果、性别及治疗结果。
