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不同年份陈化六堡茶对肥胖或超重成年人糖脂代谢、身体成分及肠道微生物群的影响:一项随机双盲研究

Effects of Liupao Tea with Different Years of Aging on Glycolipid Metabolism, Body Composition, and Gut Microbiota in Adults with Obesity or Overweight: A Randomized, Double-Blind Study.

作者信息

Wang Yuyang, Hu Qiang, Chen Botian, Ma Defu

机构信息

Department of Social Medicine and Health Education, School of Public Health, Peking University Health Science Center, Beijing 100191, China.

出版信息

Foods. 2025 Mar 3;14(5):866. doi: 10.3390/foods14050866.

DOI:10.3390/foods14050866
PMID:40077569
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11898661/
Abstract

BACKGROUND

Liupao tea (LPT) is a traditionally fermented dark tea from Guangxi, China and the effects of different aging periods of LPT on metabolic health remain inadequately explored.

METHODS

This randomized, double-blind, longitudinal study enrolled 106 adults with obesity or overweight who were assigned to consume LPT of different ages over a 90-day period. Participants were randomly divided into four groups, each consuming LPT that had been aged for 1 year, 4 years, 7 years, or 10 years. The metabolic parameters, body composition, and gut microbiota were assessed at baseline and after the 90-day intervention.

RESULTS

All LPT groups experienced significant reductions in systolic blood pressure (SBP) and diastolic blood pressure (DBP), with the 10-year-aged group showing the most notable SBP decrease ( < 0.001). Total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) levels decreased significantly in the 1-, 4-, and 10-year-aged groups ( < 0.05), while high-density lipoprotein cholesterol (HDL-C) increased in the 7-year-aged group ( < 0.05). Body weight, body fat mass (BFM), body mass index (BMI), waist circumference (WC), body fat percentage (BFP), and visceral fat area (VFA) significantly declined across all groups ( < 0.05). Gut microbiota analysis showed changes in specific genera, though overall diversity remained stable. No significant differences were found in metabolic or microbiota outcomes between the different aged groups.

CONCLUSIONS

LPT consumption effectively improves blood pressure, lipid profiles, and body composition in adults with obesity without adverse liver effects. The aging duration of LPT does not significantly alter these health benefits, challenging the belief that longer-aged LPT is superior.

摘要

背景

六堡茶是中国广西一种传统发酵黑茶,不同陈化年份的六堡茶对代谢健康的影响仍未得到充分研究。

方法

这项随机、双盲、纵向研究招募了106名肥胖或超重成年人,他们被分配在90天内饮用不同年份的六堡茶。参与者被随机分为四组,每组分别饮用陈化1年、4年、7年或10年的六堡茶。在基线和90天干预后评估代谢参数、身体成分和肠道微生物群。

结果

所有六堡茶组的收缩压(SBP)和舒张压(DBP)均显著降低,其中10年陈化组的SBP下降最为显著(<0.001)。1年、4年和10年陈化组的总胆固醇(TC)和低密度脂蛋白胆固醇(LDL-C)水平显著降低(<0.05),而7年陈化组的高密度脂蛋白胆固醇(HDL-C)升高(<0.05)。所有组的体重、体脂肪量(BFM)、体重指数(BMI)、腰围(WC)、体脂百分比(BFP)和内脏脂肪面积(VFA)均显著下降(<0.05)。肠道微生物群分析显示特定菌属发生了变化,尽管总体多样性保持稳定。不同陈化组之间在代谢或微生物群结果方面未发现显著差异。

结论

饮用六堡茶可有效改善肥胖成年人的血压、血脂谱和身体成分,且无不良肝脏影响。六堡茶的陈化时间不会显著改变这些健康益处,这对认为陈化时间越长的六堡茶越好的观点提出了挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a445/11898661/eb9313badbd2/foods-14-00866-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a445/11898661/c6b5266469a1/foods-14-00866-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a445/11898661/9915e9c855a6/foods-14-00866-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a445/11898661/a5ffd6fb0fa0/foods-14-00866-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a445/11898661/eb9313badbd2/foods-14-00866-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a445/11898661/c6b5266469a1/foods-14-00866-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a445/11898661/9915e9c855a6/foods-14-00866-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a445/11898661/a5ffd6fb0fa0/foods-14-00866-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a445/11898661/eb9313badbd2/foods-14-00866-g004.jpg

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