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沙门氏菌病诱发的心包炎和心包积液:一例病例报告及文献综述

Salmonellosis-Induced Pericarditis and Pericardial Effusion: A Case Report and Literature Review.

作者信息

Aloreibi Talal, Bukhari Emad, Terkawi Yazeed, Miqdad Mohammed A

机构信息

Infectious Diseases, Al Hammadi Hospital, Riyadh, SAU.

Cardiac Surgery, Al Hammadi Hospital, Riyadh, SAU.

出版信息

Cureus. 2025 Feb 10;17(2):e78825. doi: 10.7759/cureus.78825. eCollection 2025 Feb.

Abstract

While salmonellosis is commonly thought to predominantly impact the gastrointestinal system, bacteremia and localized extraintestinal infections such as meningitis, empyema, and pericarditis can develop, particularly in immunocompromised individuals. Here, we present a case of a 69-year-old with multiple comorbidities, who presented to the emergency department with dyspnea and hemodynamics instability in the form of hypoxia and hypotension and was found to have moderate pericardial effusion without echocardiographic signs of tamponade. The ischemic workup was unrevealing, and further infectious workups, including pericardial tissue biopsy and pericardial fluid culture, showed growth in groups C and D. Subsequently, the patient was diagnosed with -induced pericarditis and pericardial effusion and discharged home on oral antibiotics following pericardiocentesis and hemodynamics stabilization. Invasive infections caused by non-typhoidal are becoming more prevalent in immunocompromised individuals. Acute bacterial myopericarditis is uncommon in advanced nations, yet it can be life-threatening if not treated promptly. Therefore, a high index of suspicion, early detection, and aggressive invasive and non-invasive therapies would strongly be considered to achieve a desirable outcome and good prognosis.

摘要

虽然通常认为沙门氏菌病主要影响胃肠道系统,但菌血症和局部肠外感染,如脑膜炎、脓胸和心包炎也可能发生,尤其是在免疫功能低下的个体中。在此,我们报告一例69岁的患有多种合并症的患者,该患者因呼吸困难和以缺氧和低血压形式出现的血流动力学不稳定而就诊于急诊科,经检查发现有中度心包积液,但超声心动图未显示心包填塞迹象。缺血性检查未发现异常,进一步的感染性检查,包括心包组织活检和心包液培养,显示C组和D组有细菌生长。随后,该患者被诊断为非伤寒沙门氏菌引起的心包炎和心包积液,在进行心包穿刺和血流动力学稳定后,口服抗生素出院。非伤寒沙门氏菌引起的侵袭性感染在免疫功能低下的个体中越来越普遍。急性细菌性心肌心包炎在发达国家并不常见,但如果不及时治疗可能会危及生命。因此,强烈建议保持高度怀疑指数、早期检测以及积极的侵袭性和非侵袭性治疗,以实现理想的结果和良好的预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/80ad/11903102/350f5cb44393/cureus-0017-00000078825-i01.jpg

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