Kotrashetti Sharadindu M, John Shinju, Kotrashetti Vijayalakshmi, Mishra Richa, Panday Sakshi
Oral and Maxillofacial Surgery, KLE Vishwanath Katti Institute of Dental Sciences, Belagavi, IND.
Oral and Maxillofacial Pathology, Maratha Mandal's Nathajirao G. Halgekar Institute of Dental Sciences and Research Centre, Belagavi, IND.
Cureus. 2025 Feb 10;17(2):e78806. doi: 10.7759/cureus.78806. eCollection 2025 Feb.
Odontogenic keratocysts are known for their aggressive and recurrent nature. Clinically and radiographically distinguishing between ameloblastoma and odontogenic keratocysts can be challenging due to their similar locations, age of affected patients, and multilocular appearance. Ameloblastomas co-occurring with odontogenic cysts or other odontogenic lesions have been documented as combined lesions. However, unique incidences of odontogenic keratocysts showing changes of unicystic ameloblastomas are scarce, especially a large aggressive lesion occurring in the mandible extending from the molar-to-molar tooth region in a young patient as presented in this case. This transformation is rare and intriguing and warrants detailed exploration and documentation. Considering the rarity of the lesion, this case highlights the importance of considering the aggressive nature of the lesion and its transformation into ameloblastoma, cautioning the surgeon to have a long-term follow-up to evaluate recurrence and emphasizing the regeneration and restoration of quality of life in young patients.
牙源性角化囊肿以其侵袭性和复发性而闻名。由于成釉细胞瘤和牙源性角化囊肿的位置相似、患者年龄相仿以及多房性表现，在临床和影像学上区分它们具有挑战性。成釉细胞瘤与牙源性囊肿或其他牙源性病变同时出现已被记录为联合病变。然而，牙源性角化囊肿表现出单囊性成釉细胞瘤变化的独特病例很少见，尤其是在一名年轻患者中发生在下颌骨从磨牙区到磨牙区的大型侵袭性病变，如本病例所示。这种转变罕见且引人入胜，值得详细探讨和记录。鉴于该病变的罕见性，本病例强调了考虑病变的侵袭性及其向成釉细胞瘤转变的重要性，提醒外科医生进行长期随访以评估复发情况，并强调年轻患者生活质量的恢复和改善。
