Department of Medicine, Swacon International Hospital, Rudramati Marg, Kathmandu, Nepal.
Department of Medicine, All Nepal Hospital Pvt. Ltd, Samakhusi, Kathmandu, Nepal.
JNMA J Nepal Med Assoc. 2022 Jul 1;60(251):657-660. doi: 10.31729/jnma.7566.
Ameloblastomas of jaws are benign odontogenic tumors of epithelial origin with four clinical variants: solid multicystic type, unicystic type, desmoplastic type, and extraosseous type. The incidence rate of ameloblastoma is 0.92 per million person-years. Unicystic ameloblastoma refers to those cystic lesions that show clinical and radiologic characteristics of an odontogenic cyst but shows a typical ameloblastomatous epithelium lining part of the cyst cavity, with or without luminal and/or mural tumor proliferation on histological examination. Here is a unique case of unicystic ameloblastoma involving the mandible in a 70-year-old patient. The case was managed by segmental mandibulectomy and flap repair. Unicystic ameloblastoma accounts for only 13% of all known cases in scientific literature. Considering the rarity of the lesion, the purpose of presenting this report on a clinical case is to emphasize the importance of radiological evaluation and histopathological examination for the diagnosis of ameloblastoma.
ameloblastoma; odontogenic cysts; odontogenic tumors; segmental mandibulectomy.
颌骨造釉细胞瘤是来源于上皮组织的良性牙源性肿瘤，具有四种临床变异型：实性多囊型、单囊型、促结缔组织增生型和骨外型。造釉细胞瘤的发病率为 0.92/百万人年。单囊型造釉细胞瘤是指那些具有牙源性囊肿的临床和影像学特征的囊性病变，但部分囊腔衬有典型的造釉细胞瘤上皮，组织学检查可见腔内和/或壁上有肿瘤增生。这里报告了一个罕见的下颌骨单囊型造釉细胞瘤病例，患者为 70 岁女性。该病例采用节段性下颌骨切除术和皮瓣修复。单囊型造釉细胞瘤在科学文献中仅占所有已知病例的 13%。鉴于该病变罕见，因此报告该病例的目的是强调影像学评估和组织病理学检查对造釉细胞瘤诊断的重要性。
造釉细胞瘤；牙源性囊肿；牙源性肿瘤；节段性下颌骨切除术。
