de Leeuw Charles N, Ryu Won Hyung Andrew, Yoo Jung, Orina Josiah N
Department of Neurological Surgery, Oregon Health & Science University, Portland, OR, USA.
Department of Orthopaedics and Rehabilitation, Oregon Health & Science University, Portland, OR, USA.
Global Spine J. 2025 Mar 13:21925682251325823. doi: 10.1177/21925682251325823.
Study DesignA retrospective cohort utilizing the PearlDiver Patient Claims Database.ObjectiveCervical disc arthroplasty (CDA) is accepted treatment for cervical radiculopathy; however, it may also be safe and effective in myelopathy. Thus, we compared clinical characteristics and outcomes in patients undergoing CDA and anterior cervical discectomy and fusion (ACDF) for degenerative cervical myelopathy (DCM) specifically.MethodsPatients undergoing CDA or ACDF between 2015-2019 were identified with follow-up through 2021. Univariate and multivariable analyses were performed to identify factors associated with either procedure. Reoperation rates were compared using propensity-matched analysis.ResultsWe identified n = 2391 CDA and n = 50 845 ACDF procedures for DCM. Factors favoring CDA included: female sex, younger age, lower CCI, lower incidence of obesity, osteoporosis, diabetes, or smoking ( ≤ .001); remaining significant after multivariable logistic regression except for sex ( = .06). Single-level surgery was more predictive for undergoing CDA. CDA patients had lower 90-day readmissions, complications, and lower opioid utilization. The overall reoperation rate was 5%. Predictors of reoperation included: male sex, younger age, greater CCI, obesity, osteoporosis, diabetes, smoking, and multi-level surgery; all remaining significant after multivariable analysis except for diabetes ( = .23) and CCI ( = .05). After propensity-matching CDA and ACDF patients (n = 2391), there was no difference in re-operation rates ( = .47).ConclusionsCDA patients were healthier (less obesity, smoking, diabetes, better CCI) and represented 4.5% of anterior procedures for DCM. In univariate analysis, readmission rates, medical complications, and opioid use were lower in CDA patients, despite a similar reoperation rate. Considering these findings, CDA might be used very selectively for DCM.
研究设计
采用PearlDiver患者索赔数据库进行回顾性队列研究。
目的
颈椎间盘置换术(CDA)是治疗神经根型颈椎病的公认方法;然而,它对脊髓型颈椎病也可能是安全有效的。因此,我们专门比较了因退行性颈椎脊髓病(DCM)接受CDA和颈椎前路椎间盘切除融合术(ACDF)患者的临床特征和结局。
方法
确定2015年至2019年间接受CDA或ACDF治疗的患者,并随访至2021年。进行单因素和多因素分析以确定与每种手术相关的因素。使用倾向匹配分析比较再次手术率。
结果
我们确定了n = 2391例用于DCM的CDA手术和n = 50845例ACDF手术。有利于CDA的因素包括:女性、年龄较小、CCI较低、肥胖、骨质疏松症、糖尿病或吸烟的发生率较低(≤.001);多因素逻辑回归后除性别外其余因素仍具有显著性(P =.06)。单节段手术对接受CDA的预测性更强。CDA患者90天再入院率、并发症和阿片类药物使用率较低。总体再次手术率为5%。再次手术的预测因素包括:男性、年龄较小、CCI较高、肥胖、骨质疏松症、糖尿病、吸烟和多节段手术;多因素分析后除糖尿病(P =.23)和CCI(P =.05)外其余因素仍具有显著性。对CDA和ACDF患者进行倾向匹配(n = 2391)后,再次手术率没有差异(P =.47)。
结论
CDA患者健康状况更佳(肥胖、吸烟、糖尿病较少,CCI更好),占DCM前路手术的4.5%。在单因素分析中,CDA患者的再入院率、医疗并发症和阿片类药物使用较低,尽管再次手术率相似。考虑到这些发现,CDA可能非常有选择性地用于DCM。