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儿童阻塞性睡眠呼吸暂停低通气综合征的管理:正畸学的作用是什么?一项范围综述。

Management of obstructive sleep apnea-hypopnea syndrome in children: what is the role of orthodontics? A scoping review.

作者信息

Picherit Margaux, Trentesaux Thomas, Ternisien Amandine, Foumou Nathalie, Delfosse Caroline, Marquillier Thomas

机构信息

Pratique libérale pédiatrique exclusive, Rouen, F-76000 Rouen, France.

Univ. Lille, CHU Lille, Odontologie pédiatrique, Lille, F-59000, France.

出版信息

Sleep Breath. 2025 Mar 13;29(2):127. doi: 10.1007/s11325-025-03288-1.

Abstract

PURPOSE

Obstructive sleep apnoea syndrome (OSAHS) is a respiratory disorder that greatly affects the health and quality of life of patients. OSAHS affects up to 5.7% of children aged up to 18 years old, and its prevalence is doubled in children with risk factors such as obesity, craniofacial syndromes, Prader-Willi syndrome or trisomy 21. The most common aetiology of OSAHS in children is tonsil hypertrophy, and the first line treatment proposed for the majority of patients is the surgical removal of these tonsils. However, the risk of residual OSAHS after surgery is approximately 10-20%, and, thus, other therapeutic options are being developed to improve patient care. The objective of this scoping review is to assess the extent of the evidence regarding the effectiveness of the different types of treatments offered for OSAHS in children.

METHODS

Relevant studies over a 13 year period were identified using three search engines: PubMed, Scopus and Web of Science. The selection of studies was made using previously defined inclusion and exclusion criteria based on a review of the title and abstracts initially, followed by a full reading of the texts. The studies were classified based on their design and following the grades and level of scientific proof defined by the Health High Authority.

RESULTS

Twenty-nine manuscripts were included for synthesis. The first-line treatment proposed for the majority of patients with OSAHS is surgical removal of the tonsils, but the risk of residual OSAHS after surgery remains significant, and other less invasive options, such as orthodontics, are also useful for improving the management of these patients.

CONCLUSION

OSAHS treatment recommendations should consider orthodontic treatment as a minimally invasive approach with beneficial effects.

摘要

目的

阻塞性睡眠呼吸暂停低通气综合征(OSAHS)是一种严重影响患者健康和生活质量的呼吸系统疾病。OSAHS影响着高达5.7%的18岁以下儿童,在肥胖、颅面综合征、普拉德-威利综合征或21三体综合征等有危险因素的儿童中,其患病率会翻倍。儿童OSAHS最常见的病因是扁桃体肥大,大多数患者建议的一线治疗方法是手术切除这些扁桃体。然而,手术后残留OSAHS的风险约为10%-20%,因此,正在开发其他治疗选择以改善患者护理。本范围综述的目的是评估关于儿童OSAHS不同类型治疗有效性的证据范围。

方法

使用三个搜索引擎(PubMed、Scopus和Web of Science)识别了13年期间的相关研究。研究的选择最初基于对标题和摘要的审查,使用先前定义的纳入和排除标准,随后对文本进行全文阅读。根据研究设计并遵循卫生高级管理局定义的科学证据等级和水平对研究进行分类。

结果

纳入29篇手稿进行综合分析。大多数OSAHS患者建议的一线治疗方法是手术切除扁桃体,但手术后残留OSAHS的风险仍然很大,其他侵入性较小的选择,如正畸治疗,也有助于改善这些患者的治疗管理。

结论

OSAHS治疗建议应将正畸治疗视为一种具有有益效果的微创方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1960/11906523/912484993335/11325_2025_3288_Fig1_HTML.jpg

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