Lopez M, Butcher B T, Salvaggio J E, Olson J A, Reed M A, McCants M L, Lehrer S B
Int Arch Allergy Appl Immunol. 1985;77(1-2):169-70. doi: 10.1159/000233775.
Skin prick test activity and antigenicity of extracts of in vitro growth of the Basidiomycete Pleurotus ostreatus (PO) were compared to extracts of spores from PO growing in the wild. Patients demonstrated significant differences in skin test reactivity to the PO extracts. Some reacted only to in vitro growth extracts, others only to the spore extracts and 1 patient to all extracts. Further studies analyzed antigens present in all extracts with rabbit antisera to PO. Common as well as unique antigens were present in the spore extracts as compared to those from in vitro preparations. The fact that spores contain unique antigens suggests that basidiospores may be the best source of relevant allergens for clinical studies.
将平菇（PO）体外培养提取物的皮肤点刺试验活性和抗原性与野生平菇孢子提取物进行了比较。患者对平菇提取物的皮肤试验反应性存在显著差异。一些患者仅对体外培养提取物有反应，另一些仅对孢子提取物有反应，还有1名患者对所有提取物都有反应。进一步的研究用针对平菇的兔抗血清分析了所有提取物中存在的抗原。与体外培养制备的提取物相比，孢子提取物中存在共同抗原以及独特抗原。孢子含有独特抗原这一事实表明，担孢子可能是临床研究中相关过敏原的最佳来源。
