Achinger Steven G, Ayus Juan Carlos
Department of Nephrology, University of South Florida, Tampa, Florida, USA.
Department of Nephrology, Watson Clinic, LLP, Lakeland, Florida, USA.
Hemodial Int. 2025 Jul;29(3):262-274. doi: 10.1111/hdi.13225. Epub 2025 Mar 13.
Frequent (a.k.a daily hemodialysis) has continued to spark interest in the nephrology community as a way to possibly improve outcomes for the end-stage renal disease population. This is a patient population with a very high disease burden and mortality rate. The concept of dialysis adequacy in its current form has consolidated mainly around three times weekly dialysis, which has become the worldwide accepted standard. The current drive to encourage more home hemodialysis (which is a frequent dialysis regimen) has made the lessons from daily in-center hemodialysis more relevant. Frequent hemodialysis has been shown in both observational and randomized controlled studies to have some cardiovascular, mineral metabolism, and quality of life benefits. Some of what is learned from this body of literature is applicable today with increasing emphasis on home hemodialysis. This review will focus on the benefits and potential harms of daily hemodialysis to assist the practitioner in shared decision making with patients about the expected benefits and drawbacks of frequent in-center dialysis and what the expected goals should be for a frequent dialysis regimen.
频繁（即每日）血液透析作为一种可能改善终末期肾病患者预后的方法，持续引发肾脏病学界的关注。这是一个疾病负担和死亡率都非常高的患者群体。目前形式的透析充分性概念主要围绕每周三次透析而巩固，这已成为全球公认的标准。当前鼓励更多家庭血液透析（这是一种频繁透析方案）的趋势，使得从每日中心血液透析中获得的经验教训更具相关性。观察性研究和随机对照研究均表明，频繁血液透析在心血管、矿物质代谢和生活质量方面具有一些益处。从这一系列文献中学到的一些知识如今在越来越强调家庭血液透析的情况下是适用的。本综述将聚焦于每日血液透析的益处和潜在危害，以协助从业者与患者共同做出关于频繁中心透析预期益处和弊端以及频繁透析方案预期目标应是什么的决策。
