Esposito Silvano, D'Amore Chiara, Salzano Flora, Pagliano Pasquale
Unit of Infectious Diseases, Department of Medicine, Surgery and Dentistry, 'Scuola Medica Salernitana', University of Salerno, Baronissi, Italy.
UOC Clinica Infettivologica AOU San Giovanni di Dio e Ruggi d'Aragona, Salerno, Italy.
J Chemother. 2025 Mar 13:1-10. doi: 10.1080/1120009X.2025.2476830.
Mpox is an emerging zoonosis that was first described in African animals, including monkeys, small rodents, and Gambian marsupial rats. It has since been identified as a sexually transmitted infection among humans. The disease is characterized by an incubation period ranging from 5 to 21 days, with the prodromal phase typically presenting nonspecific symptoms. The incubation period is followed by the development of the characteristic vesicular skin lesions that are the hallmarks of Mpox. Over the years, small outbreaks of Mpox have occurred regularly in Central and West Africa. In July 2022, the World Health Organization (WHO) declared the outbreak a Public Health Emergency of International Concern (PHEIC), due to the rapid spread of the virus in non-endemic countries. On May 11, 2023, WHO declared the end of the Mpox emergency, considering a significant decline in reported cases. As of October 2024, the true impact of this infection on international public health remains unclear.
猴痘是一种新出现的人畜共患病，最初在非洲的动物中被发现，包括猴子、小型啮齿动物和冈比亚有袋大鼠。此后，它被确认为人类中的一种性传播感染。该疾病的潜伏期为5至21天，前驱期通常表现为非特异性症状。潜伏期过后会出现典型的水疱性皮肤损伤，这是猴痘的标志。多年来，猴痘在中非和西非定期出现小规模疫情。2022年7月，由于该病毒在非流行国家迅速传播，世界卫生组织（WHO）宣布该疫情为国际关注的突发公共卫生事件（PHEIC）。2023年5月11日，鉴于报告病例大幅下降，WHO宣布猴痘紧急情况结束。截至2024年10月，这种感染对国际公共卫生的真正影响仍不清楚。
