Rallapalle Vyshnavi, Wu Yuyuan, Curry William
Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, USA.
Birmingham VA Medical Center, University of Alabama at Birmingham, Birmingham, USA.
Cureus. 2025 Mar 12;17(3):e80480. doi: 10.7759/cureus.80480. eCollection 2025 Mar.
A Morel-Lavallée lesion (MLL) is a type of closed injury resulting in the internal shearing of superficial skin and subcutaneous tissue from the underlying fascial layer, usually occurring after traumatic accidents such as sports injuries or motor vehicle accidents. In this case, a 68-year-old man developed an MLL as a complication following a moderate-impact fall due to metformin-induced vitamin B12 deficiency. A known complication of metformin use is vitamin B12 deficiency, but this is often underdiagnosed due to a lack of routine screening. This case illustrates the importance of being aware of this complication and the many roles of vitamin B12 in terms of its effects on balance, proprioception, blood vessel integrity, and wound healing, emphasizing the importance of routine vitamin B12 screening in metformin users.
莫雷尔-拉瓦利埃损伤（MLL）是一种闭合性损伤，导致表层皮肤和皮下组织与下方筋膜层发生内部剪切，通常发生在创伤性事故之后，如运动损伤或机动车事故。在本病例中，一名68岁男性因二甲双胍诱导的维生素B12缺乏导致中度撞击跌倒后出现MLL并发症。使用二甲双胍的一个已知并发症是维生素B12缺乏，但由于缺乏常规筛查，这种情况往往诊断不足。本病例说明了认识到这种并发症的重要性，以及维生素B12在平衡、本体感觉、血管完整性和伤口愈合方面的多种作用，强调了对二甲双胍使用者进行常规维生素B12筛查的重要性。
