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使用羟基磷灰石的全颜面年轻化治疗方法:通过稀释和多层治疗方法展示羟基磷灰石多功能性的病例系列。

Panfacial Approach to Rejuvenation Using Calcium Hydroxylapatite: A Case Series Illustrating Calcium Hydroxylapatite Versatility Through Dilution and a Multilayered Treatment Approach.

作者信息

Green Jeremy B, Biesman Brian S, Hill David A, Kwok Gideon P, Levin Melissa, Sergeeva Danielle

出版信息

Aesthet Surg J Open Forum. 2024 Dec 11;7:ojae119. doi: 10.1093/asjof/ojae119. eCollection 2025.

DOI:10.1093/asjof/ojae119
PMID:40084152
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11903391/
Abstract

Dermal fillers can be used in a wide range of applications. Although the versatility of hyaluronic acid fillers stems from the wide array of available products, for the biostimulatory filler calcium hydroxylapatite (CaHA), dilution can be used to control product volumizing capacity and flow properties, facilitating use for panfacial rejuvenation. Here, the authors share case studies illustrating how CaHA at various dilutions can be used to achieve global aesthetic improvement as part of a multilayered approach to rejuvenation. As part of a continuing medical education activity, the authors treated patients with 1 to 3 sessions of CaHA at various dilutions. Six months after the patients' initial treatments, the authors reconvened to share their experiences and discuss patient results. Select case studies are presented. Though each patient recieved a unique treatment tilored to their own needs, several themes emerged. Although undiluted product can be used to provide deeper volume and structural support in areas like the chin, jawline, and temples, more dilute product (1:1 and 1:2) can be used to provide some volume and/or smooth transitions in the face, whereas hyperdilute CaHA can be used over an even wider surface area in the face, neck, or décolletage to tighten skin and improve skin quality (1:3 and 1:4 dilutions). In the cases presented, patients achieved improvement in appearance through treatment with multiple dilutions of CaHA, providing several examples of how CaHA may be used as part of a multilayered approach to facial rejuvenation.

摘要

真皮填充剂可用于广泛的应用。尽管透明质酸填充剂的多功能性源于众多可用产品,但对于生物刺激填充剂羟基磷灰石钙(CaHA)而言,稀释可用于控制产品的体积填充能力和流动性,便于用于全面部年轻化。在此,作者分享了一些案例研究,阐述了不同稀释度的CaHA如何作为多层年轻化方法的一部分用于实现整体美学改善。作为继续医学教育活动的一部分,作者用不同稀释度的CaHA对患者进行了1至3次治疗。在患者初次治疗6个月后,作者再次聚在一起分享经验并讨论患者的治疗效果。现展示部分案例研究。尽管每位患者都接受了根据自身需求定制的独特治疗,但仍出现了几个共同主题。尽管未稀释的产品可用于在下巴、下颌缘和太阳穴等部位提供更深层的体积填充和结构支撑,但更稀释的产品(1:1和1:2)可用于在面部提供一定的体积填充和/或实现平滑过渡,而超稀释的CaHA可用于面部、颈部或胸部更广泛的区域,以紧致肌肤并改善皮肤质量(1:3和1:4稀释度)。在展示的案例中,患者通过使用不同稀释度的CaHA治疗实现了外观改善,提供了几个关于CaHA如何作为面部年轻化多层方法一部分的示例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f35/11903391/b68f498f3f13/ojae119f9.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f35/11903391/a1bf819a6a70/ojae119f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f35/11903391/97f84804d508/ojae119f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f35/11903391/57840814db77/ojae119f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f35/11903391/3e3d7e47311e/ojae119f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f35/11903391/44cad69466b3/ojae119f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f35/11903391/b68f498f3f13/ojae119f9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f35/11903391/7d5855f5bea5/ojae119f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f35/11903391/5ec85289ea36/ojae119f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f35/11903391/d7a5a7218aa5/ojae119f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f35/11903391/a1bf819a6a70/ojae119f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f35/11903391/97f84804d508/ojae119f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f35/11903391/57840814db77/ojae119f6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f35/11903391/3e3d7e47311e/ojae119f7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f35/11903391/44cad69466b3/ojae119f8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f35/11903391/b68f498f3f13/ojae119f9.jpg

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本文引用的文献

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J Cosmet Dermatol. 2024 Jul;23(7):2392-2400. doi: 10.1111/jocd.16296. Epub 2024 Apr 2.
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J Cosmet Dermatol. 2024 Jun;23(6):1973-1984. doi: 10.1111/jocd.16216. Epub 2024 Feb 15.
3
Guidelines for Optimal Patient Outcomes Using Calcium Hydroxylapatite for Jawline Contour.
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Calcium hydroxylapatite microspheres activate fibroblasts through direct contact to stimulate neocollagenesis.羟基磷灰石微球通过直接接触激活成纤维细胞,刺激新胶原生成。
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