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镰状细胞危象和镰状胸综合征中的血管闭塞与梗死

Vascular occlusion and infarction in sickle cell crisis and the sickle chest syndrome.

作者信息

Athanasou N A, Hatton C, McGee J O, Weatherall D J

出版信息

J Clin Pathol. 1985 Jun;38(6):659-64. doi: 10.1136/jcp.38.6.659.

DOI:10.1136/jcp.38.6.659
PMID:4008666
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC499264/
Abstract

A young adult with homozygous sickle cell anaemia (Hb SS) suffered a fatal sickle cell crisis complicated by the sickle chest syndrome. At necropsy multiple large infarcts of the lung, bone marrow, and pituitary gland were found. The large majority of pulmonary infarcts were not associated with either gross or microscopic vaso-occlusion. These findings are discussed and correlated with past and current opinions of sickle cell crisis and the sickle chest syndrome.

摘要

一名患有纯合子镰状细胞贫血(Hb SS)的年轻成年人发生了致命的镰状细胞危象,并伴有镰状胸综合征。尸检发现肺、骨髓和垂体有多处大面积梗死。绝大多数肺梗死与大体或显微镜下的血管闭塞均无关。本文对这些发现进行了讨论,并与过去和当前关于镰状细胞危象和镰状胸综合征的观点进行了关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddbf/499264/b52384c0279f/jclinpath00189-0062-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddbf/499264/c1d8291b7aff/jclinpath00189-0060-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddbf/499264/0a5082721ef8/jclinpath00189-0060-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddbf/499264/213cd24f2b34/jclinpath00189-0061-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddbf/499264/01be88c1fcd6/jclinpath00189-0061-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddbf/499264/22dad8b77731/jclinpath00189-0061-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddbf/499264/b52384c0279f/jclinpath00189-0062-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddbf/499264/c1d8291b7aff/jclinpath00189-0060-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddbf/499264/0a5082721ef8/jclinpath00189-0060-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddbf/499264/213cd24f2b34/jclinpath00189-0061-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddbf/499264/01be88c1fcd6/jclinpath00189-0061-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddbf/499264/22dad8b77731/jclinpath00189-0061-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddbf/499264/b52384c0279f/jclinpath00189-0062-a.jpg

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本文引用的文献

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