Brignon G, Chtourou A, Ribadeau-Dumas B
J Dairy Res. 1985 May;52(2):249-54. doi: 10.1017/s0022029900024110.
Although beta-lactoglobulin (beta-lg) has been considered to be absent from human milk, recent results of other workers, based on immunological reactions between human milk and rabbit antiserum to bovine beta-lg, suggest that this protein may be present. Although our results show similar immunological reactions, we consider that lactoferrin is responsible for these, as it was the only reactive protein species which could be prepared to homogeneity. Indeed two types of antibodies were found by ELISA test in the antisera to bovine beta-lg. One of them would be able to bind loosely to human lactoferrin, but its binding sites would not be antigenic in the rabbit.
尽管一直认为人乳中不存在β-乳球蛋白（β-lg），但其他研究人员最近基于人乳与兔抗牛β-lg抗血清之间的免疫反应得出的结果表明，这种蛋白质可能存在。虽然我们的结果显示了类似的免疫反应，但我们认为乳铁蛋白是造成这些反应的原因，因为它是唯一能够制备成均一形式的反应性蛋白质种类。实际上，通过酶联免疫吸附测定（ELISA）试验在抗牛β-lg抗血清中发现了两种抗体。其中一种能够与人类乳铁蛋白松散结合，但其结合位点在兔体内不会具有抗原性。
