Hammond H K, Kelly T L, Froelicher V F, Pewen W
J Am Coll Cardiol. 1985 Jul;6(1):19-26. doi: 10.1016/s0735-1097(85)80246-1.
Fifty-nine men with coronary heart disease underwent 1 year of supervised aerobic exercise. They performed exercise tests for maximal oxygen uptake, ST segment analysis, thallium scintigraphy and radionuclide ventriculography before and after the year of exercise. A computerized data base that included clinical descriptors and exercise test results was retrospectively reviewed to determine whether initial features could predict the patient's response to the exercise intervention. Poor correlations were found between the initial measurements and change in maximal oxygen consumption and other indexes of training effect. Patients who initially were in the poorest state of fitness showed the most improvement with training. None of the initial features from the history and physical examination, treadmill study or radionuclide studies was a good predictor of a beneficial result from the exercise program. The usual measurements of work intensity during training were poor predictors of outcome. A significant decrease in the amount of ischemia measured by thallium perfusion scintigraphy was demonstrated after training.
59名冠心病男性患者接受了为期1年的有监督的有氧运动。在运动的这一年前后，他们进行了最大摄氧量运动测试、ST段分析、铊闪烁显像和放射性核素心室造影。回顾了一个包含临床描述和运动测试结果的计算机数据库，以确定初始特征是否可以预测患者对运动干预的反应。发现初始测量值与最大耗氧量的变化及其他训练效果指标之间的相关性较差。最初身体状况最差的患者在训练中改善最为明显。病史、体格检查、跑步机研究或放射性核素研究中的初始特征均不能很好地预测运动计划是否会产生有益效果。训练期间通常的工作强度测量值对结果的预测性较差。训练后铊灌注闪烁显像测量的缺血量显著减少。
