Yang Lihui, Wang Baodong, Zang Lei, Du Peng, Yuan Shuo, Fan Ning, Wu Qichao
Department of Orthopedics, Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100043, China.
J Orthop Surg Res. 2025 Mar 15;20(1):286. doi: 10.1186/s13018-025-05632-3.
The spinal endoscopic technique has been extensively documented in decompression procedures for treating lumbar degenerative diseases. However, there is limited literature on the spinal endoscopic in lumbar fusion techniques. This study evaluates the outcomes and safety of full-endoscopic posterior lumbar interbody fusion (Endo-PLIF) for the treatment of lumbar degenerative diseases.
A retrospective case series was conducted at Beijing Chaoyang Hospital, Capital Medical University, involving 43 patients who underwent Endo-PLIF between February 2020 and March 2021, with a minimum follow-up period of two years. Clinical outcomes were evaluated using the Visual Analog Scale (VAS), Oswestry Disability Index (ODI), and modified MacNab criteria. VAS and ODI scores were analyzed using one-way analysis of variance (ANOVA) at preoperative, 3-month, 12-month, 24-month, and final follow-up time points. Paired t-tests were employed to compare imaging parameters, including lumbar lordosis, disc height, segmental lordosis, and foraminal area, between the preoperative and final follow-up assessments.
This study included 43 consecutive patients with a mean age of 60.7 years and an average symptom duration of 4.6 years. All surgical procedures were successfully completed, with a mean operation duration of 233.8 ± 38.6 min. Mean VAS and ODI scores showed significant improvements postoperatively, decreasing from 7.05 ± 3.05, 7.44 ± 2.95, and 67.52 ± 9.31 points preoperatively to 1.22 ± 0.54, 1.50 ± 0.42, and 20.42 ± 3.57 at the latest follow-up (p < 0.001). Disc height (p = 0.012) and foraminal area (p = 0.013) increased significantly. MacNab evaluation indicated 90.6% of patients had good to excellent outcomes. Three patients experienced symptomatic nerve root irritation.
Endo-PLIF is safe and effective in the treatment of patients with lumbar degenerative disease in early follow-up. However, further extensive, long-term, multicenter studies are necessary to validate these findings.
脊柱内镜技术在治疗腰椎退行性疾病的减压手术中已有广泛记录。然而,关于脊柱内镜在腰椎融合技术方面的文献有限。本研究评估全内镜下腰椎后路椎间融合术(Endo-PLIF)治疗腰椎退行性疾病的疗效和安全性。
在首都医科大学附属北京朝阳医院进行了一项回顾性病例系列研究,纳入了2020年2月至2021年3月期间接受Endo-PLIF手术的43例患者,最短随访期为两年。使用视觉模拟量表(VAS)、Oswestry功能障碍指数(ODI)和改良MacNab标准评估临床疗效。在术前、术后3个月、12个月、24个月和最终随访时间点,采用单因素方差分析(ANOVA)分析VAS和ODI评分。采用配对t检验比较术前和最终随访评估之间的影像学参数,包括腰椎前凸、椎间盘高度、节段性前凸和椎间孔面积。
本研究纳入了43例连续患者,平均年龄60.7岁,平均症状持续时间4.6年。所有手术均成功完成,平均手术时间为233.8±38.6分钟。平均VAS和ODI评分术后有显著改善,从术前的7.05±3.05、7.44±2.95和67.52±9.31分降至最新随访时的1.22±0.54、1.50±0.42和20.42±3.57分(p<0.001)。椎间盘高度(p = 0.012)和椎间孔面积(p = 0.013)显著增加。MacNab评估表明90.6%的患者疗效良好至优秀。3例患者出现症状性神经根刺激。
Endo-PLIF在早期随访中治疗腰椎退行性疾病患者是安全有效的。然而,需要进一步进行广泛、长期、多中心研究来验证这些结果。