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通过儿科心包积液细胞学诊断的ALK+间变性大细胞淋巴瘤

ALK+ Anaplastic Large Cell Lymphoma Diagnosed on Paediatric Pericardial Effusion Cytology.

作者信息

Hartzell Connor, Wang Huiying, Mason Emily F, O'Conor Christopher J

机构信息

Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

出版信息

Cytopathology. 2025 May;36(3):285-289. doi: 10.1111/cyt.13481. Epub 2025 Mar 15.

DOI:10.1111/cyt.13481
PMID:40087900
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11982779/
Abstract

Authors describe pericardial effusion as the primary presentation of paediatric ALK+ ALCL, without a cardiac mass. This emphasises the diagnostic value of pericardiocentesis and highlights ALK+ ALCL in the differential diagnosis of malignant paediatric pericardial effusions.

摘要

作者描述心包积液是小儿ALK+间变性大细胞淋巴瘤（ALCL）的主要表现，且无心脏肿块。这强调了心包穿刺术的诊断价值，并突出了ALK+ALCL在小儿恶性心包积液鉴别诊断中的意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d35/11982779/8d6089f175f1/CYT-36-285-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d35/11982779/6c5a99ba16f0/CYT-36-285-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d35/11982779/8d6089f175f1/CYT-36-285-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d35/11982779/6c5a99ba16f0/CYT-36-285-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d35/11982779/8d6089f175f1/CYT-36-285-g001.jpg

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本文引用的文献

1
Primary effusion anaplastic large cell lymphoma with indolent clinical course and IRF4/DUSP22 rearrangement: a case report expanding the spectrum of effusion-based lymphoma.具有惰性临床病程及IRF4/DUSP22重排的原发性渗出性间变性大细胞淋巴瘤：1例报告，拓展基于渗出液淋巴瘤的谱型
Virchows Arch. 2023 Mar;482(3):641-645. doi: 10.1007/s00428-022-03385-6. Epub 2022 Aug 19.
2
The Epidemiology and Outcome of Pericardial Effusion in Hospitalized Children: A National Database Analysis.住院儿童心包积液的流行病学和转归：全国数据库分析。
J Pediatr. 2022 Oct;249:29-34. doi: 10.1016/j.jpeds.2022.07.005. Epub 2022 Jul 11.
3
A rare case of constrictive pericarditis as initial manifestation of paediatric anaplastic large cell lymphoma requiring urgent pericardiectomy.
一例罕见的缩窄性心包炎作为小儿间变性大细胞淋巴瘤的初始表现，需要紧急心包切除术。
Int J Surg Case Rep. 2020;73:281-284. doi: 10.1016/j.ijscr.2020.07.019. Epub 2020 Jul 16.
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Clinicopathologic analysis of malignant effusions in pediatric patients.
J Am Soc Cytopathol. 2017 Mar-Apr;6(2):41-47. doi: 10.1016/j.jasc.2016.09.002. Epub 2016 Oct 19.
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Anaplastic large cell lymphoma: pathology, genetics, and clinical aspects.间变性大细胞淋巴瘤：病理学、遗传学及临床方面
J Clin Exp Hematop. 2017;57(3):120-142. doi: 10.3960/jslrt.17023.
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Cardiac Tamponade Associated with the Presentation of Anaplastic Large Cell Lymphoma in a 2-Year-Old Child.一名2岁儿童出现间变性大细胞淋巴瘤伴发心脏压塞
Case Rep Pediatr. 2015;2015:487491. doi: 10.1155/2015/487491. Epub 2015 Sep 8.
7
Cytologic and Immunophenotypic Features of Malignant Cells in Pediatric Body Fluids.儿童体液中恶性细胞的细胞学和免疫表型特征
Acta Cytol. 2015;59(4):332-8. doi: 10.1159/000440795. Epub 2015 Oct 1.
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Anaplastic lymphoma kinase-positive anaplastic large cell lymphoma: current and future perspectives in adult and paediatric disease.间变性淋巴瘤激酶阳性间变性大细胞淋巴瘤：成人和儿童疾病的现状与未来展望
Eur J Haematol. 2014 Dec;93(6):455-68. doi: 10.1111/ejh.12360. Epub 2014 May 21.
9
Breast implant-associated anaplastic large-cell lymphoma: long-term follow-up of 60 patients.乳房植入物相关间变性大细胞淋巴瘤：60 例患者的长期随访。
J Clin Oncol. 2014 Jan 10;32(2):114-20. doi: 10.1200/JCO.2013.52.7911. Epub 2013 Dec 9.
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