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一例罕见的缩窄性心包炎作为小儿间变性大细胞淋巴瘤的初始表现，需要紧急心包切除术。

A rare case of constrictive pericarditis as initial manifestation of paediatric anaplastic large cell lymphoma requiring urgent pericardiectomy.

作者信息

Iqbal Sara, Sohail Abdul Ahad, Asif Narmeen, Khan Muhammad Rahil, Siddique Sabeehuddin, Fatimi Saulat Hasnain

机构信息

Department of Surgery, Aga Khan University Hospital (AKUH), Karachi, Pakistan.

Department of Paediatric Hematology and Oncology, The Indus Hospital, Karachi, Pakistan.

出版信息

Int J Surg Case Rep. 2020;73:281-284. doi: 10.1016/j.ijscr.2020.07.019. Epub 2020 Jul 16.

DOI:10.1016/j.ijscr.2020.07.019
PMID:32721889
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7388167/
Abstract

Constrictive pericarditis (CP) is a rare end stage inflammatory disorder affecting both parietal and visceral pericardium leading to a right heart failure. Malignancy is the least common cause of CP. Anaplastic large cell lymphoma (ALCL) accounts for 10-15% of all Non-Hodgkin lymphomas in children. Very few case reports have reported ALCL that is involving the heart and only two have been published involving pericardium but all were managed medically. We present an interesting case of an 11 year old child who presented with an effusive CP that required urgent Pericardiectomy for managing right heart failure. His histopathology was positive for ALK + ALCL.

摘要

缩窄性心包炎（CP）是一种罕见的终末期炎症性疾病，累及壁层和脏层心包，导致右心衰竭。恶性肿瘤是CP最不常见的病因。间变性大细胞淋巴瘤（ALCL）占儿童所有非霍奇金淋巴瘤的10% - 15%。很少有病例报告称ALCL累及心脏，仅有两篇报道称其累及心包，但均采用药物治疗。我们报告一例有趣的病例，一名11岁儿童表现为渗出性CP，因右心衰竭需要紧急进行心包切除术。其组织病理学检查显示ALK + ALCL呈阳性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/681a/7388167/04193bb9fe36/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/681a/7388167/cd5a35f94788/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/681a/7388167/ff958ff62202/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/681a/7388167/04193bb9fe36/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/681a/7388167/cd5a35f94788/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/681a/7388167/ff958ff62202/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/681a/7388167/04193bb9fe36/gr3.jpg

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本文引用的文献

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以缩窄性心包炎为表现的非霍奇金淋巴瘤：一例罕见病例报告
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Cardiac Tamponade Associated with the Presentation of Anaplastic Large Cell Lymphoma in a 2-Year-Old Child.一名2岁儿童出现间变性大细胞淋巴瘤伴发心脏压塞
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