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大米多孔淀粉基微胶囊化山茶油的制备、表征及其在体外消化过程中的缓释行为

Preparation, characterization and slow-release behavior during in vitro digestion of rice porous starch-based microencapsulated camellia oil.

作者信息

Wu Yingmei, Xiao WanYing, Lou Jinchen, Song Hongbo, Zhou Yan, Li Xin, Li Xiefei, An Fengping, Huang Qun, Luo Peng

机构信息

School of Public Health, the key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Province Engineering Research Center of Health Food Innovative Manufacturing, Guizhou Medical University, Guiyang 561113, China.

College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.

出版信息

Int J Biol Macromol. 2025 May;307(Pt 3):142086. doi: 10.1016/j.ijbiomac.2025.142086. Epub 2025 Mar 13.

Abstract

Microcapsules laden with camellia oil (CO), utilizing rice porous starch (PS) as the core material carrier, were successfully prepared through spray drying, employing whey protein isolate (WPI) and maltodextrin (MD) as composite wall materials. This study delved into the rheological characteristics, zeta potential, and physical stability of the CO emulsions. The results indicated a notable reduction in the apparent viscosity of the CO emulsions upon the incorporation of MD. During the WPI and MD compounding process, the W7M3 emulsions system exhibited optimal particle interactions, deformation resistance, and physical stability. Furthermore, the formation process, structural properties, and in vitro simulated digestion and release behaviors of various PS-based CO microcapsules were characterized. The encapsulation efficacy and physicochemical attributes of CO were closely associated with the characteristics of the PS carriers. FT-IR analyses confirmed the encapsulation of the essential oil in microcapsule form. PS-based microcapsules possessed a higher thermal stability. During the in vitro simulated digestion and release process, the gastric release of PS-based CO microcapsules was delayed, while the intestinal release was relatively gradual, exhibiting a superior sustained release effect. The final release amount of CO ranged between 82.60 % and 91.18 %.

摘要

以大米多孔淀粉(PS)为核心材料载体,负载山茶油(CO)的微胶囊通过喷雾干燥成功制备,采用乳清蛋白分离物(WPI)和麦芽糊精(MD)作为复合壁材。本研究深入探讨了CO乳液的流变学特性、zeta电位和物理稳定性。结果表明,加入MD后,CO乳液的表观粘度显著降低。在WPI和MD复合过程中,W7M3乳液体系表现出最佳的颗粒相互作用、抗变形能力和物理稳定性。此外,还对各种基于PS的CO微胶囊的形成过程、结构性质以及体外模拟消化和释放行为进行了表征。CO的包封率和理化性质与PS载体的特性密切相关。傅里叶变换红外光谱(FT-IR)分析证实了精油以微胶囊形式被包封。基于PS的微胶囊具有较高的热稳定性。在体外模拟消化和释放过程中,基于PS的CO微胶囊的胃内释放延迟,而肠道释放相对缓慢,表现出优异的缓释效果。CO的最终释放量在82.60%至91.18%之间。

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