Jorgensen Jennifer R, Brewer Molly A, Runowicz Carolyn D
Department of Obstetrics and Gynecology, UConn Health, 263 Farmingt6on Ave. Farmington, CT 06030, United States.
Department of Obstetrics and Gynecology, UConn Health, 263 Farmingt6on Ave. Farmington, CT 06030, United States.
Semin Perinatol. 2025 Mar;49(2):152043. doi: 10.1016/j.semperi.2025.152043. Epub 2025 Mar 13.
The objective of this manuscript is to review the epidemiology, diagnosis, treatment and outcomes of ovarian cancers diagnosed during pregnancy.
Ovarian cancer in pregnancy, although rare, is more likely to be diagnosed early during pregnancy due to the increased use of high resolution ultrasound. Treatment will depend on a multidisciplinary team. These cancers are usually treated with surgery alone during pregnancy, optimally between 13-20 weeks to reduce the risk of miscarriage or preterm labor. Chemotherapy is usually given after delivery if appropriate to the tumor type, unless the patient has widely metastatic disease.
The majority of ovarian cancers diagnosed during pregnancy are Stage I due to both young age and increased use of early ultrasound during pregnancy and have a better overall prognosis than the cancers detected in older women.
本手稿的目的是回顾孕期诊断出的卵巢癌的流行病学、诊断、治疗及预后情况。
孕期卵巢癌虽然罕见，但由于高分辨率超声使用增多，更有可能在孕期早期被诊断出来。治疗将依赖多学科团队。这些癌症在孕期通常仅通过手术治疗，最佳手术时间在13至20周之间，以降低流产或早产风险。化疗通常在分娩后根据肿瘤类型酌情使用，除非患者有广泛转移的疾病。
孕期诊断出的大多数卵巢癌因患者年轻且孕期早期超声使用增多而处于I期，总体预后比老年女性中检测出的癌症更好。
