• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

脊柱不稳定在治疗不稳定感染性骨折中的作用

The Role of Spinal Instability in Treating Unstable Infected Fractures.

作者信息

Garda James, Shah Prashant, Vance Awais Z

机构信息

Neurosurgery, Baylor College of Medicine, Temple, USA.

Cardiothoracic Surgery, Baylor Scott and White Medical Center - Temple, Temple, USA.

出版信息

Cureus. 2025 Feb 13;17(2):e78966. doi: 10.7759/cureus.78966. eCollection 2025 Feb.

DOI:10.7759/cureus.78966
PMID:40092012
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11910385/
Abstract

Vertebral (spinal) osteomyelitis is a rare spinal infection of the vertebral column that can be caused by bacteria or fungi. Though the initial treatment for all patients with vertebral osteomyelitis consists of antibiotics, surgery can be indicated in certain cases, such as in the presence of spinal instability or when antibiotics are not successfully eliminating the infection. Achieving spinal stability can be an important component of treating fracture-related infections, as instability can cause local damage and disrupt the healing process. The authors present the case of a patient with vertebral osteomyelitis that was not resolving with the administration of antibiotics in the context of a spinal fracture. A minimally invasive surgery was performed to achieve spinal stability and the infection soon resolved with antibiotics.

摘要

脊椎骨髓炎是一种罕见的脊柱感染疾病,可由细菌或真菌引起。虽然所有脊椎骨髓炎患者的初始治疗都包括使用抗生素,但在某些情况下,如存在脊柱不稳定或抗生素未能成功消除感染时,可能需要进行手术。实现脊柱稳定是治疗骨折相关感染的重要组成部分,因为不稳定会导致局部损伤并干扰愈合过程。作者介绍了一例脊椎骨髓炎患者的病例,该患者在脊柱骨折的情况下使用抗生素治疗后病情未得到缓解。通过微创手术实现了脊柱稳定,随后感染在使用抗生素后很快得到解决。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47ec/11910385/52a77e4e40ba/cureus-0017-00000078966-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47ec/11910385/7c6f68e3b02a/cureus-0017-00000078966-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47ec/11910385/79c69924ab0f/cureus-0017-00000078966-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47ec/11910385/3f8d955ea1f1/cureus-0017-00000078966-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47ec/11910385/52a77e4e40ba/cureus-0017-00000078966-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47ec/11910385/7c6f68e3b02a/cureus-0017-00000078966-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47ec/11910385/79c69924ab0f/cureus-0017-00000078966-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47ec/11910385/3f8d955ea1f1/cureus-0017-00000078966-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47ec/11910385/52a77e4e40ba/cureus-0017-00000078966-i04.jpg

相似文献

1
The Role of Spinal Instability in Treating Unstable Infected Fractures.脊柱不稳定在治疗不稳定感染性骨折中的作用
Cureus. 2025 Feb 13;17(2):e78966. doi: 10.7759/cureus.78966. eCollection 2025 Feb.
2
Posterior fixation without debridement for vertebral body osteomyelitis and discitis.椎体骨髓炎和椎间盘炎的后路固定术,不进行清创
Neurosurg Focus. 2014 Aug;37(2):E6. doi: 10.3171/2014.6.FOCUS14142.
3
Corpectomy followed by the placement of instrumentation with titanium cages and recombinant human bone morphogenetic protein-2 for vertebral osteomyelitis.椎体切除术后使用钛笼和重组人骨形态发生蛋白-2进行器械置入治疗椎体骨髓炎。
J Neurosurg Spine. 2007 Jan;6(1):23-30. doi: 10.3171/spi.2007.6.1.23.
4
Posterior Fixation Without Debridement for Vertebral Body Osteomyelitis and Discitis: A 10-Year Retrospective Review.椎体骨髓炎和椎间盘炎的后路固定术(不进行清创):一项10年的回顾性研究
Int J Spine Surg. 2023 Dec 26;17(6):771-778. doi: 10.14444/8541.
5
Current knowledge of vertebral osteomyelitis: a review.椎体骨髓炎的当前知识:综述
Eur J Clin Microbiol Infect Dis. 2025 Feb;44(2):213-231. doi: 10.1007/s10096-024-04983-9. Epub 2024 Nov 26.
6
Treatment Guideline for Patients with Native Culture-negative Pyogenic Vertebral Osteomyelitis.原发性非细菌性化脓性脊柱骨髓炎患者治疗指南。
Clin Orthop Relat Res. 2022 Jan 1;480(1):124-136. doi: 10.1097/CORR.0000000000001866.
7
[Minimal invasive surgery-transforaminal lumbar interbody fusion combined with expanded pedicle screw through Mast Quadrant channel for the treatment of senile pyogenic discitis and vertebral osteomyelitis].[微创外科——经椎间孔腰椎椎间融合术联合通过Mast Quadrant通道的膨胀椎弓根螺钉治疗老年化脓性椎间盘炎和椎体骨髓炎]
Zhongguo Gu Shang. 2019 Oct 25;32(10):937-940. doi: 10.3969/j.issn.1003-0034.2019.10.013.
8
Antibiotic-impregnated polymethylmethacrylate strut graft as a treatment of spinal osteomyelitis: case series and description of novel technique.抗生素浸渍聚甲基丙烯酸甲酯支撑移植物治疗脊柱骨髓炎:病例系列及新技术描述
J Neurosurg Spine. 2020 May 8;33(3):415-420. doi: 10.3171/2020.3.SPINE191313. Print 2020 Sep 1.
9
Direct lateral retroperitoneal approach for the surgical treatment of lumbar discitis and osteomyelitis.经直接外侧腹膜后入路手术治疗腰椎间盘炎和骨髓炎。
Neurosurg Focus. 2014 Aug;37(2):E5. doi: 10.3171/2014.6.FOCUS14150.
10
[Anterolateral decompression and three column reconstruction through posterior approach for treatment of unstable thoracolumbar fracture].[经后路前路减压及三柱重建治疗胸腰椎不稳定骨折]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2013 Jul;27(7):824-8.

本文引用的文献

1
Antibacterial Coatings for Titanium Implants: Recent Trends and Future Perspectives.钛植入物抗菌涂层:最新趋势与未来展望
Antibiotics (Basel). 2022 Nov 29;11(12):1719. doi: 10.3390/antibiotics11121719.
2
Promotion of bone formation and antibacterial properties of titanium coated with porous Si/Ag-doped titanium dioxide.多孔硅/银掺杂二氧化钛涂层钛的骨形成促进及抗菌性能
Front Bioeng Biotechnol. 2022 Oct 21;10:1001514. doi: 10.3389/fbioe.2022.1001514. eCollection 2022.
3
A state-of-the-art review of the fabrication and characteristics of titanium and its alloys for biomedical applications.
用于生物医学应用的钛及其合金的制造与特性的最新综述。
Biodes Manuf. 2022;5(2):371-395. doi: 10.1007/s42242-021-00170-3. Epub 2021 Oct 26.
4
Cobalt-Chromium Alloy Has Superior Antibacterial Effect Than Titanium Alloy: In Vitro and In Vivo Studies.钴铬合金的抗菌效果优于钛合金:体外和体内研究。
Spine (Phila Pa 1976). 2021 Sep 1;46(17):E911-E915. doi: 10.1097/BRS.0000000000003970.
5
Evidence-based uncertainty: do implant-related properties of titanium reduce the susceptibility to perioperative infections in clinical fracture management? A systematic review.循证不确定性:钛的种植体相关特性是否会降低临床骨折管理中围手术期感染的易感性?系统评价。
Infection. 2021 Oct;49(5):813-821. doi: 10.1007/s15010-021-01583-z. Epub 2021 Feb 13.
6
Titanium Kirschner Wires Resist Biofilms Better Than Stainless Steel and Hydroxyapatite-coated Wires: An Study.钛克氏针比不锈钢针和羟基磷灰石涂层针更能抵抗生物膜:一项研究。
Strategies Trauma Limb Reconstr. 2019 May-Aug;14(2):57-64. doi: 10.5005/jp-journals-10080-1426.
7
The influence of biomechanical stability on bone healing and fracture-related infection: the legacy of Stephan Perren.生物力学稳定性对骨愈合和骨折相关感染的影响:斯蒂芬·佩伦的遗产。
Injury. 2021 Jan;52(1):43-52. doi: 10.1016/j.injury.2020.06.044. Epub 2020 Jun 26.
8
[Susceptibility to infections and behavior of stainless steel : Comparison with titanium implants in traumatology].[不锈钢在创伤学中的感染易感性及性能:与钛植入物的比较]
Unfallchirurg. 2017 Feb;120(2):110-115. doi: 10.1007/s00113-016-0300-3.
9
A comparison of Staphylococcus aureus biofilm formation on cobalt-chrome and titanium-alloy spinal implants.金黄色葡萄球菌在钴铬合金和钛合金脊柱植入物上生物膜形成的比较。
J Clin Neurosci. 2016 Sep;31:219-23. doi: 10.1016/j.jocn.2016.03.013. Epub 2016 Jul 7.
10
Neurologic Complications, Reoperation, and Clinical Outcomes After Surgery for Vertebral Osteomyelitis.椎体骨髓炎手术后的神经并发症、再次手术及临床结果
Spine (Phila Pa 1976). 2016 Feb;41(4):E197-204. doi: 10.1097/BRS.0000000000001157.