Tsunematsu Oho, Takeda Shin-Ichi, Yamaguchi Mitsutaka, Kaneko Miwa, Oe Kazuho, Murakami Yoshiaki, Nagata Daisuke
Division of Nephrology, Department of Internal Medicine, Haga Red Cross Hospital, Moka, Japan.
Division of Nephrology, Department of Medicine, Jichi Medical University, Shimotsuke, Japan.
Case Rep Nephrol Dial. 2025 Feb 11;15(1):33-40. doi: 10.1159/000543999. eCollection 2025 Jan-Dec.
Constrictive pericarditis (CP) is characterized by impaired diastolic filling of the ventricles, which typically causes right heart failure. Its diagnosis may be challenging because it mimics other disorders. Furthermore, prompt diagnosis and treatment are more crucial in cases of hemodialysis; otherwise, maintenance dialysis would be hampered by severe hypotension.
We report the case of a 53-year-old man on hemodialysis who developed CP with shock. His blood pressure was 55/30 mm Hg at the time of hospitalization due to presyncope. He continued hemodialysis but with some difficulty. However, right pleural effusion persisted because of impaired fluid removal by hemodialysis. Despite such severe manifestations, the distinctive clinical features of CP were lacking. By carefully evaluating the time course of computed tomography images, progressive calcification in the pericardium emerged as a significant clue. Cardiac catheterization subsequently revealed a dip-and-plateau pattern of right ventricular pressure, which led to a definitive diagnosis of CP. Soon after the diagnosis, he underwent successful surgery.
An important finding was that, unlike calcific lesions in the general dialysis population, the patient's calcific lesions were mostly confined to the pericardium and progressed on a monthly basis. Thus, the present case may provide deep insight into the diagnosis of CP and the management of hemodialysis patients with severe hypotension.
缩窄性心包炎(CP)的特征是心室舒张期充盈受损,通常会导致右心衰竭。其诊断可能具有挑战性,因为它会模仿其他疾病。此外,在血液透析病例中,及时诊断和治疗更为关键;否则,维持性透析会因严重低血压而受阻。
我们报告了一例53岁接受血液透析的男性患者,他发生了伴有休克的CP。因先兆晕厥住院时,他的血压为55/30 mmHg。他继续进行血液透析,但有一定困难。然而,由于血液透析清除液体功能受损,右侧胸腔积液持续存在。尽管有这些严重表现,但CP的典型临床特征并不明显。通过仔细评估计算机断层扫描图像的时间进程,心包渐进性钙化成为一个重要线索。随后的心导管检查显示右心室压力呈下陷-高原型,从而明确诊断为CP。诊断后不久,他接受了成功的手术。
一个重要发现是,与一般透析人群的钙化病变不同,该患者的钙化病变大多局限于心包,且每月进展。因此,本病例可能为CP的诊断以及严重低血压血液透析患者的管理提供深刻见解。