Ragapriya K, Ajaiy M
Karpaga Vinayaga Institute of Medical Science and Research Center, Chengalpattu, India.
Indian J Otolaryngol Head Neck Surg. 2025 Mar;77(3):1478-1484. doi: 10.1007/s12070-025-05363-1. Epub 2025 Feb 8.
Dysphagia is defined as having difficulty in swallowing which may affect any part of the swallowing pathway from the mouth to stomach. Oesophageal webs are rare cause of dysphagia. It is found to occur in association with iron deficiency anaemia and dysphagia. Classical features of Plummer Vinson Syndrome include dysphagia, iron deficiency anaemia, oesophageal webs, koilonychia, angular stomatitis. Predominantly affects females past 40 years. Barium swallow and esophagoscopy shows web in the post cricoid region. About 10% of cases with this syndrome will develop post cricoid carcinoma. Treatment is to correct anaemia by oral and parenteral iron. To estimate the occurrence of anaemia and cricoid webs in patients with dysphagia attending ENT OPD in a tertiary care centre. It is a six-month observational study with 186 patients. Patients with dysphagia was further evaluated for anaemia and cricoid webs. A detailed clinical history along with blood investigations and barium swallow was done. In our study out of 186 patients with dysphagia 176 have decreased haemoglobin with decrease in serum iron and serum ferritin levels. Out of 176 only 6 patients have cricoid webs and it is commonly seen in females above 35 years. Plummer-Vinson syndrome is predominantly seen in middle aged women and present with symptoms of iron deficiency anaemia and dysphagia. Iron supplementation alone is helpful in majority of patients. PVS is a precancerous condition with high malignant potential, hence early diagnosis and regular follow up is necessary.
The online version contains supplementary material available at 10.1007/s12070-025-05363-1.
吞咽困难被定义为吞咽时有困难，这可能会影响从口腔到胃的吞咽路径的任何部分。食管蹼是吞咽困难的罕见原因。它被发现与缺铁性贫血和吞咽困难有关。普卢默-文森综合征的典型特征包括吞咽困难、缺铁性贫血、食管蹼、匙状甲、口角炎。主要影响40岁以上的女性。钡餐造影和食管镜检查显示环状软骨后区域有蹼。该综合征约10%的病例会发展为环状软骨后癌。治疗方法是通过口服和胃肠外补充铁剂来纠正贫血。为了评估在一家三级医疗中心耳鼻喉科门诊就诊的吞咽困难患者中贫血和环状软骨蹼的发生率。这是一项为期六个月的观察性研究，有186名患者。对吞咽困难的患者进一步评估贫血和环状软骨蹼情况。进行了详细的临床病史采集以及血液检查和钡餐造影。在我们的研究中，186名吞咽困难患者中有176名血红蛋白降低，同时血清铁和血清铁蛋白水平下降。在这176名患者中，只有6名有环状软骨蹼，且常见于35岁以上的女性。普卢默-文森综合征主要见于中年女性，表现为缺铁性贫血和吞咽困难的症状。仅补充铁剂对大多数患者有帮助。普卢默-文森综合征是一种具有高恶性潜能的癌前疾病，因此早期诊断和定期随访是必要的。
在线版本包含可在10.1007/s12070-025-05363-1获取的补充材料。
