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纳米乳剂的现状、热点及发展趋势:一项全面的文献计量学综述

The Current Status, Hotspots, and Development Trends of Nanoemulsions: A Comprehensive Bibliometric Review.

作者信息

Sun Guojun, Wang Liying, Dong Zuojun, Zhang Yanxiao, Yang Yan, Hu Miao, Fang Hui

机构信息

Institute of Pharmaceutical Preparations, Department of Pharmacy, Zhejiang University of Technology, Hangzhou, People's Republic of China.

Zhejiang Guangsha Vocational and Technical University of Construction, Jinhua, People's Republic of China.

出版信息

Int J Nanomedicine. 2025 Mar 11;20:2937-2968. doi: 10.2147/IJN.S502490. eCollection 2025.

Abstract

Nanoemulsions, which are characterized by their nanometer-scale droplets, have gained significant attention in different fields, such as medicine, food, cosmetics, and agriculture, because of their unique properties. With an increasing number of countries engaging in research on nanoemulsions, interest in their properties, preparation methods, and applications has increased. Hence, tracing the relevant research on nanoemulsions published in the past ten years on a global scale, by conducting data mining and visualization analysis on a sufficiently large text dataset through bibliometrics, sorting out and summarizing certain indicators, the development history, research status and research hotspots in the field of nanoemulsions can be clearly revealed, providing reference value and significance for subsequent research. This bibliometric review examines the research landscape of nanoemulsions from 2013-2023 via the SCI-E and SSCI databases, providing insights into the current status, hotspots, and future trends of this field. To offer a comprehensive overview, this analysis includes publication counts, author keywords, institutional contributions, research areas, prolific authors, highly cited papers and hot research papers. The findings reveal that China led in nanoemulsions research, followed by USA, India, and Brazil, with the University of Massachusetts emerging as a key player with the highest average number of citations per article (ACPP) and h-index. Food Chemistry, Pharmaceutics, and the Journal of Drug Delivery Science and Technology are among the top journals publishing in this area. Chemistry, pharmacology, and pharmacy emerged as the primary research domains, with McClements DJ as the most prolific and influential author. In keyword analysis, essential oil nanoemulsions are currently the main preparation direction, and various characteristics of nanoemulsions, such as their bioavailability, stability, biocompatibility, and antioxidant and antibacterial properties, have also been studied extensively. Research hotspots are focused mostly on the development of new applications and technologies for nanoemulsions.

摘要

纳米乳液以其纳米级的液滴为特征,因其独特的性质在医学、食品、化妆品和农业等不同领域受到了广泛关注。随着越来越多的国家开展纳米乳液研究,人们对其性质、制备方法和应用的兴趣也日益增加。因此,通过文献计量学对足够大的文本数据集进行数据挖掘和可视化分析,追踪过去十年全球范围内发表的有关纳米乳液的相关研究,梳理和总结某些指标,能够清晰地揭示纳米乳液领域的发展历程、研究现状和研究热点,为后续研究提供参考价值和意义。这篇文献计量学综述通过SCI-E和SSCI数据库考察了2013年至2023年纳米乳液的研究概况,深入了解该领域的现状、热点和未来趋势。为了提供全面的概述,该分析包括发表数量、作者关键词、机构贡献、研究领域、多产作者、高被引论文和热门研究论文。研究结果表明,中国在纳米乳液研究方面领先,其次是美国、印度和巴西,马萨诸塞大学成为关键参与者,其每篇文章的平均被引次数(ACPP)和h指数最高。《食品化学》《药剂学》以及《药物递送科学与技术杂志》是该领域发表论文的顶级期刊。化学、药理学和药剂学成为主要研究领域,麦克莱门茨·D·J是最多产且最具影响力的作者。在关键词分析中,精油纳米乳液目前是主要的制备方向,纳米乳液的各种特性,如生物利用度、稳定性、生物相容性以及抗氧化和抗菌性能也得到了广泛研究。研究热点主要集中在纳米乳液新应用和新技术的开发上。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bf4/11910037/5d572f013a4a/IJN-20-2937-g0001.jpg

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