嗜酸性胃肠道疾病患者中维生素缺乏的频繁报告以及补充剂和补充/替代治疗方法的使用情况。

Frequent report of vitamin deficiencies and use of supplements and complementary/alternative treatment approaches in patients with eosinophilic gastrointestinal diseases.

作者信息

Cameron Brenderia A, Jensen Elizabeth T, Dai Xiangfeng, Anderson Chelsea, Kodroff Ellyn, Strobel Mary Jo, Zicarelli Amy, Gray Sarah, Cordell Amanda, Hiremath Girish, Dellon Evan S

机构信息

Center for Esophageal Diseases and Swallowing, University of North Carolina School of Medicine, Chapel Hill, NC, USA.

Division of Gastroenterology and Hepatology, Department of Medicine, Center for Gastrointestinal Biology and Disease, University of North Carolina School of Medicine, Chapel Hill, NC, USA.

出版信息

Ther Adv Rare Dis. 2025 Mar 14;6:26330040251326928. doi: 10.1177/26330040251326928. eCollection 2025 Jan-Dec.

DOI:10.1177/26330040251326928

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11907540/

Abstract

BACKGROUND

Eosinophilic gastrointestinal diseases (EGIDs) impact nutrition.

OBJECTIVES

To assess the frequency of vitamin deficiencies, supplement use, and complementary/alternative-medication (CAM) use in EoE and non-EoE EGID patients.

DESIGN

Cross-sectional study.

METHODS

We surveyed members of EGID Partners (egidpartners.org), a patient-centered research network, to assess physician-diagnosed vitamin deficiencies, supplement use, and use of CAM in patients with EoE versus non-EoE EGIDs.

RESULTS

Of 81 EGID patients (58 EoE and 23 non-EoE EGID), self-reported frequency of vitamin deficiencies were higher in non-EoE EGIDs compared to EoE (61% vs 50%; = 0.38; Table 1). Most patients (77%) indicated taking vitamins or supplements, with higher frequency in non-EoE EGID cases (87% vs 72%; = 0.16). Use of >30 different supplements was reported. For CAM, herbal approaches were more frequent in non-EoE EGIDs compared to EoE (26% vs 5%; = 0.008).

CONCLUSION

Vitamin deficiencies and supplement/CAM use are frequent in EGIDs, highlighting the need for additional EGID treatment.

摘要

背景

嗜酸性粒细胞性胃肠道疾病（EGIDs）会影响营养状况。

目的

评估嗜酸性食管炎（EoE）和非EoE的EGID患者中维生素缺乏、补充剂使用及补充和替代医学（CAM）使用的频率。

设计

横断面研究。

方法

我们对以患者为中心的研究网络EGID Partners（egidpartners.org）的成员进行了调查，以评估经医生诊断的EoE患者与非EoE的EGID患者的维生素缺乏情况、补充剂使用情况及CAM使用情况。

结果

在81例EGID患者（58例EoE和23例非EoE的EGID）中，自我报告的维生素缺乏频率在非EoE的EGID患者中高于EoE患者（61%对50%；P = 0.38；表1）。大多数患者（77%）表示服用维生素或补充剂，非EoE的EGID病例中服用频率更高（87%对72%；P = 0.16）。报告使用了30多种不同的补充剂。对于CAM，非EoE的EGID患者中使用草药疗法的频率高于EoE患者（26%对5%；P = 0.008）。

结论

EGIDs患者中维生素缺乏以及补充剂/CAM的使用很常见，这凸显了对EGIDs进行更多治疗的必要性。