Moraresku Sofiia, Hammer Jiri, Dimakopoulos Vasileios, Kajsova Michaela, Janca Radek, Jezdik Petr, Kalina Adam, Marusic Petr, Vlcek Kamil
Laboratory of Neurophysiology of Memory, Institute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Third Faculty of Medicine, Charles University, Prague, Czechia.
Neurosci Bull. 2025 Mar 17. doi: 10.1007/s12264-025-01371-x.
The dorsal and ventral visual streams have been considered to play distinct roles in visual processing for action: the dorsal stream is assumed to support real-time actions, while the ventral stream facilitates memory-guided actions. However, recent evidence suggests a more integrated function of these streams. We investigated the neural dynamics and functional connectivity between them during memory-guided actions using intracranial EEG. We tracked neural activity in the inferior parietal lobule in the dorsal stream, and the ventral temporal cortex in the ventral stream as well as the hippocampus during a delayed action task involving object identity and location memory. We found increased alpha power in both streams during the delay, indicating their role in maintaining spatial visual information. In addition, we recorded increased alpha power in the hippocampus during the delay, but only when both object identity and location needed to be remembered. We also recorded an increase in theta band phase synchronization between the inferior parietal lobule and ventral temporal cortex and between the inferior parietal lobule and hippocampus during the encoding and delay. Granger causality analysis indicated dynamic and frequency-specific directional interactions among the inferior parietal lobule, ventral temporal cortex, and hippocampus that varied across task phases. Our study provides unique electrophysiological evidence for close interactions between dorsal and ventral streams, supporting an integrated processing model in which both streams contribute to memory-guided actions.
背侧通路被认为支持实时动作，而腹侧通路则促进记忆引导的动作。然而，最近的证据表明这些通路具有更整合的功能。我们使用颅内脑电图研究了在记忆引导动作过程中它们之间的神经动力学和功能连接。在一项涉及物体识别和位置记忆的延迟动作任务中，我们追踪了背侧通路中下顶叶小叶、腹侧通路中腹侧颞叶皮层以及海马体的神经活动。我们发现，在延迟期间，两条通路的阿尔法波功率均增加，表明它们在维持空间视觉信息方面的作用。此外，我们记录到在延迟期间海马体的阿尔法波功率增加，但仅在需要同时记住物体识别和位置时出现。我们还记录到在编码和延迟期间，下顶叶小叶与腹侧颞叶皮层之间以及下顶叶小叶与海马体之间的theta波段相位同步增加。格兰杰因果分析表明，下顶叶小叶、腹侧颞叶皮层和海马体之间存在动态的、频率特异性的方向相互作用，且这种相互作用在不同任务阶段有所变化。我们的研究为背侧和腹侧通路之间的紧密相互作用提供了独特的电生理证据，支持了一种整合处理模型，即两条通路都对记忆引导的动作有贡献。
