Cetinkaya Onur, Arslan Ulku, Temel Hakan, Kavakli Ali Sait, Cakin Hakan, Cengiz Melike, Yilmaz Murat, Barcin Nur Ebru, Ikiz Fatih
Department of Anesthesiology and Reanimation, Akdeniz University Faculty of Medicine, Antalya 07070, Turkey.
Department of Anesthesiology and Reanimation, Istinye University Faculty of Medicine, Istanbul 34010, Turkey.
J Clin Med. 2025 Feb 28;14(5):1650. doi: 10.3390/jcm14051650.
Spontaneous subarachnoid haemorrhage (SAH) represents a significant cerebrovascular disease with considerable morbidity and mortality. The aim of this study was to determine the demographic/clinical characteristics of spontaneous SAH patients admitted in the intensive care unit (ICU) and factors affecting the mortality. This study was designed as a retrospective cohort study that included patients with a diagnosis of spontaneous SAH hospitalized in the ICU. The clinical and radiological parameters were compared between mortality and survival cohorts. Univariate logistic regression analyses were performed for the effect profiles of the parameters on mortality. ICU mortality was 41% in patients with spontaneous SAH. A number of factors have been identified as being independently associated with mortality in the studied cohort. These factors are hospital admission with loss of consciousness (Glasgow Coma Scale score <8), a high Clinical Comorbidity Index score, stage >2 according to the Hunt and Hess grading system and complication status (meningitis and sepsis/septic shock). Spontaneous SAH is a condition associated with a high mortality in severe cases. Patients exhibiting these risk factors require meticulous monitoring in the ICU.
自发性蛛网膜下腔出血（SAH）是一种严重的脑血管疾病，具有较高的发病率和死亡率。本研究的目的是确定入住重症监护病房（ICU）的自发性SAH患者的人口统计学/临床特征以及影响死亡率的因素。本研究设计为一项回顾性队列研究，纳入了在ICU住院且诊断为自发性SAH的患者。对死亡队列和存活队列的临床和放射学参数进行了比较。对各参数对死亡率的影响情况进行了单因素逻辑回归分析。自发性SAH患者的ICU死亡率为41%。在该研究队列中，已确定一些因素与死亡率独立相关。这些因素包括入院时意识丧失（格拉斯哥昏迷量表评分<8）、临床合并症指数评分高、根据Hunt和Hess分级系统处于>2期以及并发症情况（脑膜炎和脓毒症/感染性休克）。自发性SAH在严重病例中是一种与高死亡率相关的疾病。表现出这些危险因素的患者在ICU需要进行细致的监测。
