Sharman Jeremy, Turner Natasha, Karahalios Amalia, Sansom Ben, Deane Adam M, Plummer Mark P
Intensive Care Unit, Royal Melbourne Hospital, Melbourne, VIC, Australia.
Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC, Australia.
J Intensive Care Soc. 2024 Dec 2;26(1):47-52. doi: 10.1177/17511437241301916. eCollection 2025 Feb.
Advanced age is an independent risk factor for poor outcomes following aneurysmal subarachnoid haemorrhage (SAH). However, Australian data are lacking. Our aim was to evaluate outcomes for older patients admitted to an Australian intensive care unit for management of aneurysmal SAH.
We conducted a single centre retrospective observational study looking at adult patients admitted with aneurysmal SAH to an Intensive Care Unit (ICU) over a 10-year period. Patients were grouped by age; <70 years, 70-79 years, ⩾80 years, and were of sufficient complexity to be unsuitable for our neurosurgical high-dependency unit. The primary outcome was in-hospital mortality. Secondary outcomes were ICU and hospital length of stay, and discharge destination.
Of 372 patients admitted to ICU with aneurysmal SAH, 302 (82%) were younger (<70 years), 46 (12%) were septuagenarians and 24 (6%) were octogenarians. There were no differences between clinical or radiological grade of aneurysmal SAH between age cohorts. When compared to the patients younger than 70 years, there was increased odds of dying for those 70-79 and ⩾80 years (70-79: OR 1.98, 95% CI 0.93, 4.20 = 0.077; ⩾80: OR 4.01, 95% CI 1.55, 10.35 = 0.004). There were no associations between age and duration of admission. Only 6% of patients aged ⩾70 years were discharged home alive.
It was uncommon for patients over 70 years of age who present with a SAH to be discharged home from hospital, and those aged ⩾80 are four times more likely to die in hospital than younger patients.
高龄是动脉瘤性蛛网膜下腔出血(SAH)后预后不良的独立危险因素。然而,澳大利亚缺乏相关数据。我们的目的是评估入住澳大利亚重症监护病房接受动脉瘤性SAH治疗的老年患者的预后。
我们进行了一项单中心回顾性观察研究,观察10年间入住重症监护病房(ICU)的动脉瘤性SAH成年患者。患者按年龄分组:<70岁、70 - 79岁、≥80岁,且病情复杂程度足以不适合进入我们的神经外科高依赖病房。主要结局是院内死亡率。次要结局是ICU住院时间、住院时间和出院去向。
在372例入住ICU的动脉瘤性SAH患者中,302例(82%)年龄较轻(<70岁),46例(12%)为七十多岁患者,24例(6%)为八十多岁患者。各年龄组之间动脉瘤性SAH的临床或放射学分级无差异。与70岁以下患者相比,70 - 79岁和≥80岁患者死亡几率增加(70 - 79岁:比值比1.98,95%置信区间0.93,4.20 ,P = 0.077;≥80岁:比值比4.01,95%置信区间1.55,10.35 ,P = 0.004)。年龄与住院时间无关联。70岁及以上患者中只有6%存活出院回家。
70岁以上SAH患者出院回家并不常见,80岁及以上患者在医院死亡的可能性是年轻患者的四倍。