Villafuerte Kelly Rocio V, Palucci Vieira Luiz Henrique, Santos Karina O, Rivero-Contreras Edgard, Lourenço Alan Grupioni, Motta Ana Carolina F
Grupo de Investigación Salud Integral Humana (GISIH), Faculty of Health Sciences, Universidad César Vallejo (UCV), Callao Campus, Lima 07001, Peru.
Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo (USP), Bauru 17012-901, SP, Brazil.
J Clin Med. 2025 Mar 1;14(5):1680. doi: 10.3390/jcm14051680.
: To systematically evaluate scientific evidence related to the influence of psychological stress on the response to periodontal treatment. : PubMed/NCBI (National Center for Biotechnology Information, US National Library of Medicine), Web of Science (ClarivateTM), EBSCOHost, SCOPUS, and ProQuest databases were searched for published clinical studies in English up to May 2024. The quality of each study was assessed using the Ottawa-Newcastle scale. : Of 803 relevant articles identified, 8 were included in the qualitative synthesis qualitative synthesis. These studies involved 445 patients who completed the follow-up period, ranging from 6 weeks to 6 months. Stressed patients were more likely to experience higher levels of PPD and BOP compared to non-stressed patients. In total, 75% of the included studies showed a positive relationship between stress and response to NSPT, 12.5% observed a negative relationship, and the remaining 12.5% found some degree of relationship in the results of clinical periodontal parameters. The level of evidence is categorized according to the quality of the synthesis presented. : There is a positive correlation between psychological stress and periodontal treatment response, indicating that stress may negatively influence the clinical outcomes of NSPT. Stress may reduce the inflammatory response, which is crucial for eliminating periodontal micropathogens after periodontal treatment.
系统评价心理应激对牙周治疗反应影响的相关科学证据。检索了PubMed/NCBI（美国国立医学图书馆国家生物技术信息中心）、Web of Science（科睿唯安公司）、EBSCOHost、SCOPUS和ProQuest数据库，以查找截至2024年5月发表的英文临床研究。使用渥太华-纽卡斯尔量表评估每项研究的质量。在识别出的803篇相关文章中，8篇被纳入定性综合分析。这些研究涉及445名完成随访期的患者，随访期从6周到6个月不等。与无应激患者相比，应激患者更有可能出现更高水平的探诊深度（PPD）和探诊出血（BOP）。总共，75%的纳入研究显示应激与非手术牙周治疗（NSPT）反应之间存在正相关，12.5%观察到负相关，其余12.5%在临床牙周参数结果中发现了一定程度的相关性。证据水平根据所呈现综合分析的质量进行分类。心理应激与牙周治疗反应之间存在正相关，表明应激可能对NSPT的临床结果产生负面影响。应激可能会降低炎症反应，而炎症反应对于牙周治疗后消除牙周微病原体至关重要。
